Results 51 to 60 of about 10,411 (162)

Shared dysregulation of complement and phosphorylation pathways in the cerebrospinal fluid of encephalitis, Aicardi–Goutières syndrome, and autism

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To identify shared and disorder‐specific molecular alterations across encephalitis, Aicardi–Goutières syndrome (AGS), and autism spectrum disorder (ASD) using cerebrospinal fluid (CSF) proteomics. Method In this cross‐sectional case–control study, mass‐spectrometry‐based proteomics was performed on archived CSF samples collected between ...
Omar H. Shadid, Peter G. Hains, Velda X. Han, Jingya Yan, Michael Griffiths, Ignatius Pang, Sushil Bandodkar, Phillip J. Robinson, Russell C. Dale   +8 more
wiley   +1 more source

Neopterin, β2-Microglobulin, Tryptophan and Kynurenine In Sporadic Amyotrophic Lateral Sclerosis

Pteridines, 1994
In 62 patients diagnosed as sporadic amyotrophic lateral sclerosis (sALS), we quantitated serum concentrations of neopterin, β2-microglobulin. kynurenine and tryptophan.
Westarp Martin E., Fuchs Dietmar, Westarp Maria P., Wachter Helmut, Kornhuber Hans-Helmut   +4 more
doaj   +1 more source

Bidirectional interaction between ferroptosis and chronic fatigue syndrome: Insights into neuroinflammation and oxidative stress

Brain‐X, Volume 4, Issue 3, September 2026.
The potential connection between chronic fatigue syndrome (CFS) and ferroptosis has been explored within the mechanisms of neuroinflammation and oxidative stress, revealing that the occurrence of intracellular ferroptosis may be one of the crucial mechanisms leading to the onset of CFS.
Guiping Wang, Peipei Guo, Cong Liu, Heng Tang, Yuanyuan Fan, Can Mei, Yujia Xu, Zijun Shi, Linwanyue Chen, Weiji Zhou, Qing Xu, Yuchen Huang, Tao Huang, Bin Deng, Jianbo Zhan, Jing Cheng   +15 more
wiley   +1 more source

Nailfold capillary phenotypes distinguish juvenile myositis subtypes and associate with disease activity

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Nailfold capillaroscopy is a non‐invasive imaging tool that can aid in the diagnosis and monitoring of juvenile myositis. Branched nailfold capillary morphology is more common in juvenile myositis patients, particularly those positive for TIF1γ+ autoantibodies. Juvenile myositis patients with more active disease demonstrate increased microhaemorrhages,
Nicholas McClellan, Li Chen, Sophia Matossian, Aurora Rynda, Kirsten Grant, Erin Janssen, J. Michelle Kahlenberg, Jessica L. Turnier   +7 more
wiley   +1 more source

Immunologic markers of progression to acquired immunodeficiency syndrome are time-dependent and illness-specific [PDF]

, 1992
Krämer A, Biggar RJ, Hampl H, et al. Immunologic markers of progression to acquired immunodeficiency syndrome are time-dependent and illness-specific. American Journal of Epidemiology.
Biggar, Robert J., Hampl, Hartmut, Fuchs, Dietmar, Krämer, Alexander ; https://orcid.org/, Goedert, James J., Friedman, Robert M., Wachter, Helmut   +6 more
core  

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

Annals of Clinical and Translational Neurology, Volume 13, Issue 8, Page 1702-1710, August 2026.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez, Monica Ferrer Socorro, Kathryn Yang, Nicole Battaglia, Zainab Zaman, Mariko Bennett, Adeline Vanderver, Pui Y. Lee, Lauren A. Henderson, Milena M. Andzelm, Darius Ebrahimi‐Fakhari   +10 more
wiley   +1 more source

Influence of Three Different Diet Modes Combined with Exercise Loads on Urinary and Plasma Neopterin Concentrations: A Longitudinal Study

Pteridines, 1997
During six months, we studied the influence of three extremely different diet modes (normal diet, carbohydrate- rich diet, fat-rich diet) combined with three defined exercise loads (step test, endurance test fo r 30 minutes, endurance test for 90 minutes)
Lamprecht Manfred, Mlekusch Walter, Vrecko Karoline, Reibnegger Gilbert   +3 more
doaj   +1 more source

The relationship between plasma level of indoleamine 2,3-dioxygenase and neopterin in patients with depression

Psychiatry and Clinical Psychopharmacology, 2021
Objective: Preliminary results of the study that intended to compare serum indoleamine 2,3-dioxygenase (IDO) and neopterin levels in patients with major depression and the healthy control group is presented.
Adem Balıkcı, Murat Erdem, Abdullah Bolu, Tuncer Çaycı, Emre Aydemir, A. Gazi Ünlü, Emin Özgür Akgül   +6 more
doaj  

Targeted Interventions in HAM/TSP: Emerging Therapies and Future Directions – A Narrative Review

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aim Human T‐Lymphotropic virus type 1 (HTLV‐1) infection can lead to HTLV‐1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP), a debilitating chronic neurological disease characterized by progressive lower limb spasticity and autonomic dysfunction.
Meygol Mirzaei Rezaei, Mahdi Khosravi Nia, Kasra Allaei Rouzbahani, Maryam Kazemi, Negar Asghari Hosori, Mehdi Norouzi, Farzaneh Sotoudegan, Narges Eslami, Negar Ariamand, Vahid Shahnavaz, Arash Letafati, Sayed‑Hamidreza Mozhgani   +11 more
wiley   +1 more source

Neopterin extends C. elegans lifespan in an ATFS-1-dependent manner

microPublication Biology
Neopterin, a byproduct of tetrahydrobiopterin synthesis, is commonly used as a biomarker for immune system activation. In addition to its role in immune responses, neopterin levels are known to increase with age. Its impact on longevity, however, remains
Miina Pitkänen, Geoffray Monteuuis, Christopher B. Jackson, Olli Matilainen   +3 more
doaj   +1 more source