Results 81 to 90 of about 13,713 (220)

Clinical Value of Neopterin In Infectious Complications

open access: yesPteridines, 1999
Neopterin, a pteridine intermediate metabolite in the biopterine synthetic pathway, is synthesized and secreted by monocyte/macrophages upon stimulation, mainly by gamma-interferon by activated T cells.
Iwagaki Hiromi   +5 more
doaj   +1 more source

Increasing Tetrahydrobiopterin in Cardiomyocytes Adversely Affects Cardiac Redox State and Mitochondrial Function Independently of Changes in NO Production [PDF]

open access: yes, 2016
Tetrahydrobiopterin (BH4) represents a potential strategy for the treatment of cardiac remodeling, fibrosis and/or diastolic dysfunction. The effects of oral treatment with BH4 (Sapropterin™ or Kuvan™) are however dose-limiting with high dose negating ...
Bennett, Brian   +5 more
core   +1 more source

Adult‐Onset Acute Cerebellar Ataxia with Preceding Essential Tremor‐like Syndrome Associated with a Novel Variant in ATP1A3

open access: yes
Movement Disorders Clinical Practice, Volume 13, Issue 3, Page 832-834, March 2026.
Lukas Gattermeyer‐Kell   +6 more
wiley   +1 more source

Diagnosis of tetrahydrobiopterin deficiency using filter paper blood spots: further development of the method and 5 years experience [PDF]

open access: yes, 2018
In every newborn with even mild hyperphenylalaninemia (HPA) tetrahydrobiopterin (BH4) deficiencies need to be excluded as soon as possible. Differential diagnosis is most commonly performed by analysis of urinary neopterin and biopterin.
Abu Seda, Bettina   +5 more
core  

The physiological and mononuclear cell activation response to cryotherapy following a mixed martial arts contest: a pilot study

open access: yesPteridines, 2015
Cold water immersion is thought to reduce the inflammatory response to injury. Using cultured mononuclear cells and human subjects in a mixed martial arts (MMA) contest, we examined the effect of cryotherapy on 7,8-dihydroneopterin and neopterin ...
Lindsay Angus   +7 more
doaj   +1 more source

Clinical importance of serum neopterin level in patients with pulmonary tuberculosis

open access: yesInternational Journal of Mycobacteriology, 2014
Objective: Neopterin is a sensitive marker for cell-mediated immune response. Because of this, the neopterin levels of body fluids show cell-mediated immune response in different infectious diseases which involve T cells and macrophages.
Salih Cesur   +7 more
doaj   +1 more source

Neopterin Serum sebagai Prediktor Dini Luaran Perburukan pada Sepsis Neonatorum

open access: yesGlobal Medical & Health Communication, 2017
Abstrak Neopterin telah diketahui sebagai biomarker untuk diagnostik sepsis neonatorum awitan dini. Hingga saat ini belum diketahui peran neopterin sebagai biomarker untuk memprediksi luaran sepsis neonatorum awitan dini maupun awitan lanjut.
Ahmad Hafidz   +2 more
doaj  

Urinary Neopterin in Patients with Advanced Colorectal Carcinoma

open access: yesThe International Journal of Biological Markers, 2006
In previous studies, mostly in patients with early stage colorectal carcinoma, neopterin, an indicator of systemic immune activation, has been associated with poor prognosis. The aim of the present study was to evaluate urinary neopterin in patients with
B. Melichar MD, PhD   +5 more
doaj   +1 more source

The role of neopterin in cross-talk between tumor and tumor microenvironment in hepatocellular carcinoma

open access: yesPteridines
Neopterin is a marker of activated immune response, but its role in hepatocarcinogenesis is unknown. The present study aims to evaluate the effects of neopterin on prooncogenic/proinflammatory, apoptotic pathways, and other molecular mechanisms in HCC ...
Satılmış Basri   +6 more
doaj   +1 more source

Follow-up of Urinary Neopterin Concentrations in two Healthy Children until Adolescence

open access: yesPteridines, 2003
Neopterin is a sensitive marker of the activated cellular (= Thl-type) immune response. Neopterin concentrations in healthy children are higher compared with those of adults and are declining with increasing age.
Winkler Christiana   +4 more
doaj   +1 more source

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