Urinary Neopterin in Patients with Advanced Colorectal Carcinoma
In previous studies, mostly in patients with early stage colorectal carcinoma, neopterin, an indicator of systemic immune activation, has been associated with poor prognosis. The aim of the present study was to evaluate urinary neopterin in patients with
B. Melichar MD, PhD +5 more
doaj +2 more sources
Neopterin as a diagnostic biomarker for diagnosis of inflammatory diseases like periodontitis
Neopterin is a catabolic product of guanosine triphosphate, a purine nucleotide and belongs to the group pteridines. When the cytokine interferon gamma stimulates the human macrophages, they synthesize the neopterin.
Jammula Surya Prasanna +2 more
doaj +2 more sources
Longitudinal changes in plasma biomarkers of immune activation, neuronal inflammation and injury in persons with HIV initiating ART. [PDF]
Abstract Background Data on changes in biomarkers of brain health, and their associations with cognitive function in adults commencing either dual‐ or triple‐antiretroviral therapy (ART) are sparse. Methods Plasma biomarkers (neurofilament light [NfL], glial fibrillary acidic protein [GFAP], sCD14, CXCL10, neopterin and IL‐6) were measured at baseline ...
Henderson M +13 more
europepmc +2 more sources
Effects of extreme mountain ultramarathon on stress-related biomarkers from multiple biological matrices in adult male runners. [PDF]
Abstract Prior investigations concerning finishers of the Tor des Géants (TDG) have demonstrated oxi‐inflammatory response. MicroRNAs (miRNAs) have been identified as prospective biomarkers for oxi‐inflammatory and stress responses. This study addressed the acute responses concerning salivary miRNAs, circulating redox markers and urinary exercise ...
Purcaro C +7 more
europepmc +2 more sources
An Overview of Pterin Analysis in Biological Samples: From Occurrence and Properties to Sample Pretreatment Combined With Hyphenated Separation Techniques. [PDF]
ABSTRACT Pterins are a structurally diverse group of biologically active compounds within the pteridine family, with key roles in pigmentation, redox metabolism, light sensing, and cellular signaling across a wide range of organisms. Their quantification in biological samples is analytically demanding due to their high polarity, chemical instability ...
Brejcha J, Bosakova Z.
europepmc +2 more sources
EVALUATION OF NEOPTERIN AS A PROGNOSTIC MARKER FOR SEVERITY OF PNEUMONIA IN PEDIATRICS [PDF]
Background: The aim of this study was to investigate the role of Neopterin in evaluation of severity and outcome of pneumonia in pediatric Department of Zagazig University Hospitals.Methods: A prospective case control study was carried out at the ...
Mahmoud Rabie +3 more
doaj +1 more source
Efficient Total Syntheses of Natural Neopterin Glycosides: Neopterin Glucronide and Solfapterin [PDF]
1’,2’-Di-O-acetyl-N2-(N,N-dimethylaminomethylene)-3-[2-(4-nitro- phenyl)ethyl]neopterin (11a) and its 1’,2’-di-O-benzoyl analog (11b) were prepared from neopterin in 5 steps, respectively.
Hanaya, Tadashi +7 more
core +2 more sources
Neopterin and [beta]2-microglobulin as prognostic indices in human immunodeficiency virus type 1 infection [PDF]
Fuchs D, Krämer A, Reibnegger G, et al. Neopterin and [beta]2-microglobulin as prognostic indices in human immunodeficiency virus type 1 infection. Infection.
Werner, Ernst R. +13 more
core +1 more source
Urinary neopterin concentrations and T-cell subset data in HIV-1 infection [PDF]
Reibnegger G, Fuchs D, Goedert JJ, et al. Urinary neopterin concentrations and T-cell subset data in HIV-1 infection. Journal of Molecular Medicine. 1990;68(1):43-48.We investigated the ability of urinary neopterin concentrations and T-cell subset data ...
Werner, Ernst R. +8 more
core +1 more source
Objective: The aim of this study was to examine the activity of immune system in patients with major depression by using serum neopterin levels as a biochemical tool.
Cemil Çelik +5 more
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