Results 11 to 20 of about 9,485 (209)

Urinary Neopterin in Malignant Lymphoma

The International Journal of Biological Markers, 1991
Urinary neopterin levels were studied in 96 patients with malignant lymphomas. Twenty-eight had Hodgkin's disease and 68 non-Hodgkin's lymphoma. Neopterin excretion was significantly related to the clinical stage of the disease.
L. Piccinini, S. Zironi, M. Federico, L. A. Pini, G. Luppi   +4 more
doaj   +5 more sources

Urinary neopterin concentrations vs total neopterins for clinical utility. [PDF]

Clinical Chemistry, 1989
Abstract Neopterin measurements are especially useful as an early marker in (e.g.) allograft rejections and in patients infected with human immunodeficiency virus type 1 (HIV-1). An increased concentration of total neopterins (neopterin + dihydroneopterin) is also a significant marker in patients with HIV-1 infection.
Fuchs, Dietmar, Milstien, Sheldon, Krämer, Alexander, Reibnegger, Gilbert, Werner, Ernst R., Goedert, James J., Kaufman, Seymour, Wachter, Helmut   +7 more
openaire   +5 more sources

Detection of neopterin in tear samples

Pteridines, 2016
The main goal of the present study was to detect neopterin concentrations in human tear samples and to evaluate its potential correlation with serum neopterin levels.
Baydar Terken, Kemer Ozlem Evren, Kilicarslan Bilge, Cardak Aziz, Girgin Gözde   +4 more
doaj   +2 more sources

Neopterin Counters Vascular Inflammation and Atherosclerosis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundNeopterin, a metabolite of GTP, is produced by activated macrophages and is abundantly expressed within atherosclerotic lesions in human aorta and carotid and coronary arteries.
Remina Shirai, Kengo Sato, Tomoyuki Yamashita, Maho Yamaguchi, Taisuke Okano, Kaho Watanabe‐Kominato, Rena Watanabe, Taka‐aki Matsuyama, Hatsue Ishibashi‐Ueda, Shinji Koba, Youichi Kobayashi, Tsutomu Hirano, Takuya Watanabe   +12 more
doaj   +2 more sources

Serum Neopterin Levels among Hepatitis C-Positive Living-Donor Renal Transplant Recipients

Biomarker Insights, 2015
Background The role of neopterin as a marker of cell-mediated immunity for immunological monitoring after transplantation is of great potential interest.
Shivali Justa, Ranjana W. Minz, Shashi Anand, Mukut Minz   +3 more
doaj   +2 more sources

Plasma total neopterin and neopterin levels are significantly elevated in stroke patients before carotid endarterectomy surgery

Pteridines
Atherosclerosis is an inflammatory disease where activated immune cells are recruited into the artery wall forming artery plaques. Interferon-γ released by T-cells causes macrophage synthesis and release of 7,8-dihydroneopterin, an antioxidant and CD36 ...
Raajasekar Siddarth, Roake Justin, Cameron Vicky, Benson Ruth, Pilbrow Anna, Gieseg Steven   +5 more
doaj   +2 more sources

Cytokine induction of neopterin production

Clinical and Experimental Immunology, 1991
SUMMARYThe pteridine neopterin is a marker of immunological activation and has been shown to be a useful marker of graft-versus-host disease (GVHD) in bone marrow transplant patients. High levels of both neopterin and interferon-gamma (IFN-γ) were produced in vitro during mixed lymphocyte responses, which may be considered to be a model of the primary ...
D C, Henderson, J, Sheldon, P, Riches, J R, Hobbs   +3 more
openaire   +4 more sources

Neopterin Determinations in Tuberculous Bone Infections

Pteridines, 1994
In patients with tuberculous chest infections caused by intracellular Mycobacteria elevated serum neopterin levels could be found. In the present study neopterin levels were elevated in 5/6 patients with proven tuberculous bone infections as well ...
Peters K. M., Schweitzer K., Zimmermann S., Zilkens K. W.   +3 more
doaj   +2 more sources

The Predictive Value of Tenascin-C, Neopterin and Pro-Inflammatory Cytokines (IFN-γ, TNF-α, IL-6) in Alcohol Use Disorder Treatment Response. [PDF]

Addict Biol
Thirty patients with AUD undergoing detoxification and 31 healthy controls were evaluated. From baseline to day 7, TNC decreased significantly, accompanied by improvements in depression, anxiety and total symptom scores. Neopterin and cytokine levels remained unchanged.
Akpinar G, Sener G, Altunkiliç EF, Yazgec E, Ozturk AB, Basan NM, Ozsemerci HA.   +6 more
europepmc   +2 more sources

Longitudinal changes in plasma biomarkers of immune activation, neuronal inflammation and injury in persons with HIV initiating ART. [PDF]

HIV Med
Abstract Background Data on changes in biomarkers of brain health, and their associations with cognitive function in adults commencing either dual‐ or triple‐antiretroviral therapy (ART) are sparse. Methods Plasma biomarkers (neurofilament light [NfL], glial fibrillary acidic protein [GFAP], sCD14, CXCL10, neopterin and IL‐6) were measured at baseline ...
Henderson M, Dutey-Magni P, Herrera C, Stöhr W, Arenas-Pinto A, Swann O, Heslegrave A, Zetterberg H, Tregoning J, Fidler S, Raffi F, Calcagno A, Babiker A, Winston A.   +13 more
europepmc   +2 more sources