Results 11 to 20 of about 13,713 (220)

Neopterin, Inflammation, and Oxidative Stress: What Could We Be Missing?

Antioxidants, 2018
Neopterin has been extensively used as a clinical marker of immune activation during inflammation in a wide range of conditions and stresses. However, the analysis of neopterin alone neglects the cellular reactions that generate it in response to ...
Steven P. Gieseg, Gregory Baxter-Parker, Angus Lindsay   +2 more
doaj   +3 more sources

Neopterin measurement in clinical diagnosis [PDF]

Journal of Clinical Pharmacy and Therapeutics, 2001
Neopterin is a marker associated with cell-mediated immunity. It is produced in monocytes/macrophages primarily upon stimulation with interferon-gamma. Due to its chemical structure, neopterin belongs to the class of pteridines. It is excreted in an unchanged form via the kidneys. Serum levels above 10 nmol/L are regarded as elevated.
A, Berdowska, K, Zwirska-Korczala
openaire   +4 more sources

Expansion of neopterin and beta2-microglobulin in cerebrospinal fluid reaches maximum levels early and late in the course of human immunodeficiency virus infection [PDF]

, 1992
Inhaltsverzeichnis ...
Bogner, Johannes R., Goebel, Frank-Detlef, Junge-Hülsing, B., Kronawitter, Ursula, Matuschke, A., Sadri, Ifna   +5 more
core   +1 more source

Cerebrospinal Fluid Concentrations of the Synaptic Marker Neurogranin in Neuro-HIV and Other Neurological Disorders. [PDF]

, 2019
Purpose of reviewThe aim of this study was to examine the synaptic biomarker neurogranin in cerebrospinal fluid (CSF) in different stages of HIV infection and in relation to what is known about CSF neurogranin in other neurodegenerative diseases.Recent ...
Blennow, Kaj, Fuchs, Dietmar, Gisslén, Magnus, Price, Richard W, Spudich, Serena, Yilmaz, Aylin, Zetterberg, Henrik   +6 more
core   +2 more sources

Fibroblast growth factors 1 and 2 in cerebrospinal fluid are associated with HIV disease, methamphetamine use, and neurocognitive functioning. [PDF]

, 2016
BackgroundHuman immunodeficiency virus (HIV) and methamphetamine use commonly affect neurocognitive (NC) functioning. We evaluated the relationships between NC functioning and two fibroblast growth factors (FGFs) in volunteers who differed in HIV ...
Bharti, Ajay R, Cherner, Mariana, Ellis, Ronald J, Everall, Ian P, Grant, Igor, Heaton, Robert K, Letendre, Scott L, Masliah, Eliezer, Potter, Michael, Rosario, Debra, Woods, Steven Paul   +10 more
core   +2 more sources

Treatment of major depression with sertraline: Relationship between serum neopterin levels and respond to the treatment

Psychiatry and Clinical Psychopharmacology, 2021
Objective: The aim of this study was to examine the activity of immune system in patients with major depression by using serum neopterin levels as a biochemical tool.
Cemil Çelik, Murat Erdem, Barbaros Özdemir, Tuncer Çaycı, Türker Türker, Fuat Özgen   +5 more
doaj  

The challenging problem of disease staging in human African trypanosomiasis (sleeping sickness): a new approach to a circular question [PDF]

, 2017
Human African trypanosomiasis (HAT), also known as sleeping sickness, puts millions of people at risk in sub-Saharan Africa and is a neglected parasitic disease that is almost always fatal if untreated or inadequately treated. HAT manifests itself in two
Gettinby, George, Kennedy, Peter G.E., Njamnshi, Alfred K.   +2 more
core   +1 more source

Rapid Diagnostic Algorithms as a Screening Tool for Tuberculosis: An Assessor Blinded Cross-Sectional Study [PDF]

, 2012
Background: A major obstacle to effectively treat and control tuberculosis is the absence of an accurate, rapid, and low-cost diagnostic tool. A new approach for the screening of patients for tuberculosis is the use of rapid diagnostic classification ...
A Ali-Gombe, A Fares, A Sita-Lumsden, A Ustianowski, Alexandra Indra, B Thiede, Bernhard Parschalk, BJ Marais, C Lange, CC Boehme, CJ Clopper, CK Liam, D Agranoff, Delmiro Fernandez-Reyes, E Harju, Franz Ratzinger, G Walzl, H Getahun, Harald Bruckschwaiger, Heimo Lagler, J Nemeth, J Zhang, K Fassbender, KP Cain, M Glennon, M Sester, Martin Wischenbart, MB Miller, MD Perkins, Michael Ramharter, Olivier Neyrolles, OP Sharma, P Papay, R McNerney, S Le Cessie, Sanjeev Krishna, SB Kotsiantis, Stefan Winkler, SV Balasingham, T Fawcett, T Tanaka, Wolfgang Graninger   +41 more
core   +9 more sources

Urinary Neopterin in Patients with upper Gastrointestinal, Biliary and Pancreatic Carcinomas

Pteridines, 2006
Increased urinary neopterin has been associated with advanced disease and poor prognosis in patients with colorectal carcinoma, but less is known about urinary neopterin in other gastrointestinal tumors.
Melichar Bohuslav, Solichová Dagmar, Svobodová Ivcta, Urbánek Lubor, Melicharová Karolina   +4 more
doaj   +1 more source

Biomarkers of Tuberculosis Severity and Treatment Effect: A Directed Screen of 70 Host Markers in a Randomized Clinical Trial. [PDF]

, 2017
More efficacious treatment regimens are needed for tuberculosis, however, drug development is impeded by a lack of reliable biomarkers of disease severity and of treatment effect. We conducted a directed screen of host biomarkers in participants enrolled
Barbero, S, Davis, J, Haynesworth, K, Jacobs, J, Jarlsberg, L, Lewinsohn, D, Mathew, A, Nahid, Payam, Schorey, J, Segal, Mark, Sigal, G, Small, N, Wang, M, Weiner, M, Whitworth, W   +14 more
core   +2 more sources