Results 21 to 30 of about 2,873 (175)

Disorders of biopterin metabolism [PDF]

Journal of Inherited Metabolic Disease, 2009
SummaryDefects in the metabolism or regeneration of tetrahydrobiopterin (BH4) were initially discovered in patients with hyperphenylalaninaemia who had progressive neurological deterioration despite optimal metabolic control (malignant hyperphenylalaninaemia).
openaire   +2 more sources

Enhanced Monacolin K Production in Monascus purpureus Via Mutagenesis and Nitrogen Source Optimization. [PDF]

J Basic Microbiol
ABSTRACT Monascus fungi are valued for their production of Monacolin K (MK), a bioactive compound with recognized lipid‐lowering and multifunctional properties. To enhance MK yield in solid‐state fermentation, this study combined atmospheric and room‐temperature plasma (ARTP) mutagenesis with L‐arginine supplementation.
Yang C, Yajing Y, Housheng H.
europepmc   +2 more sources

Effect of 7,8 -Dihydroneopterin, Biopterin and Isoxanthopterin on Cholesterol and Phospholipid Content and Phospholipid Biosynthesis in Vitro

Pteridines, 1996
Incorporation of fatty acids into phospholipids has been investigated using samples of rat liver tissue homogenate (Krebs-Ringer-phosphate buffer, pH=7.4, containing 0.3% albumin, fatty acid mixture and glycerol). The addition of 7,8-dihydroneopterin and
Rudzite Vera, Jurika Edite, Baier-Bitterlich Gabriele, Wachterl Helmut, Fuchs Dietmar   +4 more
doaj   +1 more source

Chemical structure of 1-O-(L-erythro-biopterin-2'-yl)-a-glucose isolated from a cyanobacterium Synechococcus sp. PCC 7942

Pteridines, 2001
A pteridine glycoside in Synechococcus sp. PCC 7942, the structure of which had been tentatively identified as biopterin-glucoside, was isolated and characterized for its exact chemical structure by 2D-NMR spectroscopy. The determined structure is 1-0-(L-
Choi Yong Kee, Hwang Yoon Kyung, Kang Yong Han, Park Young Shik   +3 more
doaj   +1 more source

Neopterin and Cytokines in Hereditary Dystonia and Parkinson's Disease

Pteridines, 1999
Both neopterin and biopterin concentrations in cerebrospinal fluid from patients with Parkinson's disease, in which the nigrostriatal dopamine neurons degenerate, were lower than those from age-matched older control subjects.
Nagatsu T., Ichinose H., Mogi M., Togari A.   +3 more
doaj   +1 more source

The urinary biopterin in autism spectrum disorder

Pteridines, 2021
The aim of the study was to determine whether biopterin is present in significantly lower quantities in urine samples of patients with autism spectrum disorder (ASD) compared to healthy individuals.
Waligóra Aleksandra, Damasiewicz-Bodzek Aleksandra, Gorczyca Piotr, Waligóra Sławomir, Tyrpień-Golder Krystyna   +4 more
doaj   +1 more source

Biosynthetic Enzymes of Tetrahydrolimipterin from Green Sulfur Bacterium Chlorobium Limicola

Pteridines, 1998
Based on the structure of limipterin (Cha, Pfleiderer, and Yim, Helv, Chim. Acta, 78: 600-614. 1995 the biosynthetic pathway for the newly identified pterin glycoside was investigated. It was demonstrated that tetrahydrolimipterin (H4 -limipterin) can be
Kang Dongmin, Kim Sangjoon, Yim Jeongbin
doaj   +1 more source

Data‐Driven Insights into Hyperkinetic Disorders in Neurodevelopmental Syndromes and Epileptic Encephalopathies

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Childhood‐onset hyperkinetic movement disorders occur in a range of genetic conditions. Recently, there has been an increase in recognition of hyperkinetic movement disorders, mainly dystonia, chorea and dyskinesia, with monogenic conditions associated with neurodevelopmental delay (NDD) and also with developmental and epileptic ...
Hugo Morales‐Briceño, Shekeeb S. Mohammad, Rajeshwar Reddy Angiti, Velda Han, Michel Tchan, Russell C. Dale, Victor S.C. Fung   +6 more
wiley   +1 more source

Immunological impact of tetrahydrobiopterin on the central nervous system in a murine model of rabies virus infection

Revista do Instituto de Medicina Tropical de São Paulo, 2021
Currently, the Milwaukee protocol presents healing results in human beings affected by the rabies virus. However, there are many points to clarify on the action of drugs and the immune mechanism involved in the evolution of the disease.
Caio Vinicius Botelho Brito, Érika Dayane Leal Rodrigues, Fernanda Monik Silva Martins, Lavinia Dias Tavares, André Luis de Sousa Nogueira Lima, Lucas Carvalho Ferreira, Carlos Junior Lopes Santana, João Augusto Gomes de Souza Monteiro de Brito, Lívia Medeiros Neves Casseb, José Antonio Picanço Diniz Junior   +9 more
doaj   +1 more source

eQTL Meta‐Analysis Reveals Conserved and Population‐Specific Regulatory Variation Underlying Nutritional Trait Evolution and Domestication in Tomato

Advanced Science, Volume 13, Issue 44, 7 August 2026.
A comprehensive meta‐analysis of expression quantitative trait loci (eQTLs) across five diverse tomato populations reveals a high‐resolution atlas of transcriptional regulation and uncovers conserved and population‐specific regulatory architectures underlying fruit nutritional quality traits, including flavonoids, sugars, organic acids, carotenoids ...
Jiantao Zhao, Xin Wang, Jing Zhang, Ryan McQuinn, Je Min Lee, Itay Gonda, Ari Feder, Yimin Xu, Baike Wang, Qinghui Yu, Denise M. Tieman, Sanwen Huang, Harry Klee, James J. Giovannoni, Zhangjun Fei   +14 more
wiley   +1 more source