Results 41 to 50 of about 6,178 (219)

Ethnic Bridging of Sepiapterin in Chinese and Korean Populations Based on Predictions From Genetic Polymorphism of Breast Cancer Resistance Protein

Clinical and Translational Science, Volume 19, Issue 4, April 2026.
ABSTRACT Ethnic differences are crucial when considering the efficacy, safety, and dose of pharmaceuticals across diverse populations. The International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use (ICH) guideline E5 addresses the acceptability of extrapolating foreign clinical data taking ethnic factors into ...
Lan Gao, Neil Smith, Ronald Kong
wiley   +1 more source

Evaluation of Serum and Urinary Levels of some Pteridine Pathway Components in Healthy Turkish Children

Pteridines, 2012
Neopterin, as a non-conjugated pteridine, is synthesized from guanosine triphosphate and its production is upregulated upon the activation of cellular immune response.
Girgin Gözde, Baydar Terken, Fuchs Dietmar, Sahin Gönül, Özmert Elif, Yurdakök Kadriye   +5 more
doaj   +1 more source

A Simple Method for RNA‐Seq of Manually Isolated Chromatophores in Oryzias Fishes

Development, Growth &Differentiation, Volume 68, Issue 3, April 2026.
ABSTRACT RNA sequencing (RNA‐seq) has become an essential tool for analyzing gene expression and exploring cell type–specific transcriptomes. However, sample preparation and quality control remain challenging, as current approaches typically rely on dissecting tissues containing mixed cell populations or using flow cytometry to isolate fluorescently ...
Makoto Goda, Asuka Miyagi, Keisuke Sugiwaka, Masakatsu Watanabe, Manabu Bessho‐Uehara, Masahiko Hibi, Atsushi Toyoda, Rieko Tanaka, Kawilarang W. A. Masengi, Kazunori Yamahira, Satoshi Ansai, Hisashi Hashimoto   +11 more
wiley   +1 more source

Electronic Structure of Tetrahydropteridine Derivatives

Pteridines, 1999
Recently; the 4-amino analogue of tetrahydrobiopterin was found to be a strong inhibitor of nitric oxide synthase while being bound to the enzyme in a manner similar to the natural cofactor tetrahydrobiopterin.
Reibnegger Gilbert, Pauschenwein Jutta, Werner Ernst R.   +2 more
doaj   +1 more source

Alternative cancer therapy through modeling pteridines photosensitizer quantum yield singlet oxygen production using swarm-based support vector regression and extreme learning machine

Cogent Engineering
Photodynamic cancer therapy circumvents the major side effects associated with the conventional cancer treatment methods, such as chemotherapy, surgery and exposure to radiation.
Nahier Aldhafferi
doaj   +1 more source

Pterin function in bacteria

Pteridines, 2017
Pterins are widely conserved biomolecules that play essential roles in diverse organisms. First described as enzymatic cofactors in eukaryotic systems, bacterial pterins were discovered in cyanobacteria soon after.
Feirer Nathan, Fuqua Clay
doaj   +1 more source

When Pathways Converge: Iron, Lipid Peroxidation, and α‐Synuclein in Ferroptosis‐Driven Dopaminergic Neurodegeneration

Journal of Neurochemistry, Volume 170, Issue 4, April 2026.
Dopaminergic neurons are particularly susceptible to ferroptosis. Pacemaking activity–driven calcium (Ca2+) influx increases metabolic demand and reactive oxygen species (ROS) production, promoting iron release from aconitase. Alpha‐synuclein (α‐syn) enhances iron uptake via transferrin receptor 1 (TfR1) and exhibits ferrireductase activity, converting
Carmem L. Sperlich, Brent R. Stockwell, Marcelo Farina   +2 more
wiley   +1 more source

Theoretical study on the relative energies of cationic pterin tautomers

Pteridines, 2015
Pterins are heterocyclic molecules of biological importance that contain several basic sites. These molecules can be protonated in aqueous solution resulting in a wide variety of structures that differ in their site of protonation and tautomeric form. In
Nekkanti Sindhura, Martin Christopher B.
doaj   +1 more source

Studies on the Feculae of Selected Michigan Acrididae (Orthoptera) [PDF]

, 2017
Feculae have been used for some years in the study of insect food-habits and biology. Among the past authors who have used them are Frost (1928), Hodson and Brooks (1956), and Morris (1942), who discussed the use of feculae and frass in the ...
Gangwere, S.K., Tyrkus, Michael
core   +3 more sources

Synthesis of Peptides, Peptide Nucleic Acid Components, and Other Biogenic Compounds From a Three‐Component Prebiotic Mixture

Chemistry – A European Journal, Volume 32, Issue 9, 2 March 2026.
High‐energy proton irradiation of a formamide–diaminomaleonitrile–glycine system in the presence of meteorites produces a broad spectrum of biogenic compounds, including nucleobases, nucleosides, peptides, and nucleobase–peptide conjugates, highlighting a chemically plausible prebiotic network.
Bruno Mattia Bizzarri, Rosangela Santalucia, Eleonora Mancin, Mikhail Kapralov, Eugene Krasavin, Raffaele Saladino, Ernesto Di Mauro   +6 more
wiley   +1 more source