Results 51 to 60 of about 3,953 (191)

Investigations on the Luminescence Behavior of a Flavin Derivative Incorporated Into Al‐Based Metal–Organic Frameworks for the Sensing of Aromatic Nitro Compounds

Zeitschrift für anorganische und allgemeine Chemie, Volume 652, Issue 14, 23 September 2026.
For nitro group‐containing volatile compounds, a quenching effect was observed for DAMI@MOF, while the non‐nitro compounds chlorobenzene, toluene, and benzene yielded a fluorescence enhancement, rationalized by the relative energies of the derivative 8‐(dimethylamino)‐10‐methylisoalloxazine (DAMI) and analyte S1 states, with concomitant opposite ...
Annette Vollrath, Vasily Gvilava, Philipp Seiffert, Constantin Czekelius, Christoph Janiak   +4 more
wiley   +1 more source

Pyridyl‐Thiazole‐Thiosemicarbazones as Antitrypanosomatidae Agents: Design, Synthesis, and In Silico Profiling

ChemMedChem, Volume 21, Issue 16, 27 August 2026.
A novel pyridine–thiazole derivative, Compound 8, exhibited potent dual antitrypanosomatid activity. It demonstrated remarkable in vitro efficacy against Trypanosoma cruzi (IC50 = 1.0 µM) and L. amazonensis (IC50 = 3.9 µM). Molecular docking studies suggested interactions with heme and multiple molecular targets.
Anderson José Firmino Santos da Silva, Daiane Santiago da Cruz Olimpio, Lucas Manoel da Silva Sousa, Graziella Leite Brondani, Tacylla Lima Silva, Wéllyda Belmira de Lira Silva, Natáli Tereza Capistrano Costa, Marcelo Zaldini Hernandes, Policarpo Ademar Sales Junior, Valéria Rêgo Alves Pereira, Ana Cristina Lima Leite   +10 more
wiley   +1 more source

Evaluation of Serum and Urinary Levels of some Pteridine Pathway Components in Healthy Turkish Children

Pteridines, 2012
Neopterin, as a non-conjugated pteridine, is synthesized from guanosine triphosphate and its production is upregulated upon the activation of cellular immune response.
Girgin Gözde, Baydar Terken, Fuchs Dietmar, Sahin Gönül, Özmert Elif, Yurdakök Kadriye   +5 more
doaj   +1 more source

Electronic Structure of Tetrahydropteridine Derivatives

Pteridines, 1999
Recently; the 4-amino analogue of tetrahydrobiopterin was found to be a strong inhibitor of nitric oxide synthase while being bound to the enzyme in a manner similar to the natural cofactor tetrahydrobiopterin.
Reibnegger Gilbert, Pauschenwein Jutta, Werner Ernst R.   +2 more
doaj   +1 more source

Pteridines in the Control of Pigmentation

Journal of Investigative Dermatology, 1997
The influence of UVB irradiation on the metabolic pathway for the production of L-tyrosine from L-phenylalanine in the human epidermis has been examined in 12 healthy volunteers with photo skin types I-VI (Fitzpatrick classification). This metabolic pathway involves the induction of GTP-cyclohydrolase 1 (GTP-CH-1), the rate-limiting enzyme for de novo ...
Schallreuter, Karin U., Schulz-Douglas, Vincent, Bünz, Andreas, Beazley, Wayne, Körner, Christa   +4 more
openaire   +2 more sources

From o‐Phenylenediamine to Flavin Derivatives: A Potential Prebiotic Carbon Skeleton Expansion With Formaldehyde, Cyanide, and CO2

Advanced Synthesis &Catalysis, Volume 368, Issue 16, 18 August 2026.
A Strecker‐type reaction of aromatic ortho‐diamines with various aldehydes and cyanide assembles the bicyclic amidine core of flavin‐derived heterocycles under mild conditions. Subsequent oxidation, radical or photochemical cyanation, carboxylation with CO2, and CO2‐mediated cyclization build the three‐ring alloxazine scaffold. This sequence provides a
Christian Held, Rodrigo José da Silva Lima, Ji‐Woong Lee   +2 more
wiley   +1 more source

Daily Variation and Effect of Dietary Folate on Urinary Pteridines

, 2016
Introduction: Urinary pteridines are putative molecular biomarkers for noninvasive cancer screening and prognostication. Central to their translational biomarker development is the need to understand the sources and extent of their non-epidemiological ...
Shi, Honglan, Casey Burton, Ma, Yinfa, Honglan Shi, Burton, Casey, Yinfa Ma   +5 more
core   +1 more source

Alternative cancer therapy through modeling pteridines photosensitizer quantum yield singlet oxygen production using swarm-based support vector regression and extreme learning machine

Cogent Engineering
Photodynamic cancer therapy circumvents the major side effects associated with the conventional cancer treatment methods, such as chemotherapy, surgery and exposure to radiation.
Nahier Aldhafferi
doaj   +1 more source

Pterin function in bacteria

Pteridines, 2017
Pterins are widely conserved biomolecules that play essential roles in diverse organisms. First described as enzymatic cofactors in eukaryotic systems, bacterial pterins were discovered in cyanobacteria soon after.
Feirer Nathan, Fuqua Clay
doaj   +1 more source

Theoretical study on the relative energies of cationic pterin tautomers

Pteridines, 2015
Pterins are heterocyclic molecules of biological importance that contain several basic sites. These molecules can be protonated in aqueous solution resulting in a wide variety of structures that differ in their site of protonation and tautomeric form. In
Nekkanti Sindhura, Martin Christopher B.
doaj   +1 more source