Results 51 to 60 of about 3,922 (190)
Theoretical study on the relative energies of cationic pterin tautomers
Pterins are heterocyclic molecules of biological importance that contain several basic sites. These molecules can be protonated in aqueous solution resulting in a wide variety of structures that differ in their site of protonation and tautomeric form. In
Nekkanti Sindhura, Martin Christopher B.
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Photo-reduction of Pteridines [PDF]
WHEN a solution of 7-hydroxypteridine1 was spotted on a sheet of Whatman No. 1 filter paper, irradiated with ultra-violet light (principally 254 mµ) for 5 min., and developed (by ascending chromatography) in various solvents, two spots appeared. One of these was identical with the starting material (unirradiated material was used as a control on the ...
openaire +2 more sources
ABSTRACT The leopard coral grouper, Plectropomus leopardus Lacepède, 1802, is an ecologically and economically important species in the family Epinephelidae. However, the absence of a complete reference genome has impeded advanced genetic research on this species, and the phylogenetic position of Epinephelidae within Perciformes remains unresolved ...
Baojun Zhao +8 more
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Aim: The aim of the study was to determine whether orthotopic liver transplantation leads to the activation of macrophages, neutrophils and complement.
Tomasdottir H. +3 more
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A Recessive oca2 Mutation Underlies Albinism in Xiphophorus Fish
Genetic mapping of albino Xiphophorus hellerii showed that albinism is associated with a recessive oca2 variant. This variant leads to early termination of the Oca2 protein. This study identifies a novel model system to investigate conserved mechanisms of pigmentation biology.
Yanting Xing +5 more
wiley +1 more source
Pteridines, LXXVII. C-Acylations of Pteridines by Homolytic Heteroaromatic Substitution [PDF]
Homolytic substitution reactions with acyl radicals proceed with 2,4-diamino- (VI-VIlI) and 4-amino-2-methylthiopteridines (XXVII-XX IX) selectively at position 7 to give the corresponding 7-acyl derivatives IX-XV and XXX-XXXV, respectively, in moderate ...
Baur, Ralph +5 more
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Soluble Fas ligand and neopterin in patients with systemic and cutaneous discoid lupus erythematosus
Evidence accumulates suggesting that the pathogenesis in systemic lupus erythematosus (SLE) is associated with modulations in the Fas/FasL system. Serum concentrations of soluble Fas ligand (sFasL) were found to be elevated in patients with SLE.
Wirleitner Barbara +6 more
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Role of Weak Molecular Interactions in the Mechanism of Action of a Series of Antihelmintics
Different physicochemical properties such as solute-solute and solute-solvent interactions, tautomerism, lipophilicity and solubility in water were determined for a serie of 6,7-diaryl-pteridines in order to relate those properties with their nematocide ...
Marisa Santo +7 more
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Capture‐SELEX of DNA Aptamers for Highly Selective Binding of Folate
Using capture‐SELEX, a DNA aptamer with sub‐micromolar affinity for folate was isolated, showing excellent selectivity. Using this aptamer, a light‐up fluorescent biosensor was developed for folate detection. Folate (vitamin B9) is an essential micronutrient for human health, particularly during pregnancy.
Yachen Xie, Yifan Chen, Juewen Liu
wiley +1 more source
This study integrated bioinformatics analysis, cellular models, and PD/constipation mouse models to identify SHMT2 as a key shared biomarker linking Parkinson's disease and constipation. SHMT2 upregulation was validated in dopaminergic neurons and the enteric nervous system, highlighting its potential role in gut–brain axis dysfunction.
Jiehua Su +10 more
wiley +1 more source

