Results 51 to 60 of about 6,178 (219)

Release of Neopterin, PMN Elastase and Terminal Complement Complexes by Orthotopic Liver Transplantation with and without the Use of Veno-venous Bypass

open access: yesPteridines, 1998
Aim: The aim of the study was to determine whether orthotopic liver transplantation leads to the activation of macrophages, neutrophils and complement.
Tomasdottir H.   +3 more
doaj   +1 more source

Exploring Novel Nitrofuryl‐1,3,4‐Thiadiazole‐Based Derivatives: Design, Synthesis, and Evaluation of In Vitro Leishmanicidal and Trypanocidal Activity

open access: yesArchiv der Pharmazie, Volume 359, Issue 3, March 2026.
In a series of substituted 1‐[5‐(5‐nitrofuran‐2‐yl)‐1,3,4‐thiadiazol‐2‐yl]piperidine‐4‐carboxamides evaluated for in vitro antileishmanial and antitrypanosomal activity, compound 18 emerged as the most promising derivative, showing submicromolar anti‐parasitic effects targeting diverse Leishmania and Trypanosoma species and acceptable selectivity ...
Alireza Mousavi   +17 more
wiley   +1 more source

Soluble Fas ligand and neopterin in patients with systemic and cutaneous discoid lupus erythematosus

open access: yesPteridines, 2000
Evidence accumulates suggesting that the pathogenesis in systemic lupus erythematosus (SLE) is associated with modulations in the Fas/FasL system. Serum concentrations of soluble Fas ligand (sFasL) were found to be elevated in patients with SLE.
Wirleitner Barbara   +6 more
doaj   +1 more source

Role of Weak Molecular Interactions in the Mechanism of Action of a Series of Antihelmintics

open access: yesMolecules, 2000
Different physicochemical properties such as solute-solute and solute-solvent interactions, tautomerism, lipophilicity and solubility in water were determined for a serie of 6,7-diaryl-pteridines in order to relate those properties with their nematocide ...
Marisa Santo   +7 more
doaj   +1 more source

Negligible effects of tryptophan on the aflatoxin adsorption of sodium bentonite [PDF]

open access: yes, 2014
The main objective of this study was to determine if the competitive adsorption of tryptophan (Trp) and aflatoxin B1 (AFB1) could potentially affect the ability of a sodium bentonite (NaB) to prevent aflatoxicosis in monogastric animals.
Chiacchiera, Stella Maris   +5 more
core   +1 more source

Synthesis of 7-Acyl-2,4-disubstituted Pteridines by Radical Nucleophilic Substitution and Displacement Reactions

open access: yesPteridines, 2004
2,4-Disubstituted pteridine derivatives (1-3) react with acyl radicals very selectively in position 7 by a nucleophilic Substitution mechanism (4-10).
Döring Thomas   +2 more
doaj   +1 more source

Age‐Dependent Variation in Blood Biopterin Peaks Following Oral Tetrahydrobiopterin Administration in Phenylketonuria

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT The correct diagnosis of tetrahydrobiopterin (BH4, sapropterin dihydrochloride)‐responsive phenylketonuria (PKU) and treatment with BH4 are important for prognosis and quality of life. We examined whether age affects biopterin bioavailability following oral BH4 administration in PKU and whether this influences BH4 responsiveness.
Kana Kitayama   +5 more
wiley   +1 more source

Tetrahydrobiopterin analogues with NO-dependent pulmonary vasodilator properties [PDF]

open access: yes, 2011
Reduced NO levels due to the deficiency of tetrahydrobiopterin (BH4) contribute to impaired vasodilation in pulmonary hypertension Due to the chemically unstable nature of BH4 it was hypothesised that oxidatively stable analogues of BR, would be able to ...
Gibson, Colin   +4 more
core   +1 more source

A Twenty Year Association with Pteridines - Chemistry, Biochemistry and Molecular Biology

open access: yesPteridines, 1998
The author has summarised the science in his published works which contained chemistry. biochemistry and molecular biology related to pteridines as a dedication to Professor Wolfgang Pfleiderer on the occasion of his seventieth birthday.
Armarego Wilfred L. F.
doaj   +1 more source

Pigment composition of the bright skin in the poison toad, Melanophryniscus rubriventris (Anura: Bufonidae) from Argentina [PDF]

open access: yes, 2017
The determination of the basis of skin colour is important to better understand the evolutionary and ecological relevance of colour variation in aposematic species.
Bonansea, Maria Ines   +2 more
core  

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