Results 61 to 70 of about 3,589 (204)
Journal of Neurochemistry, Volume 170, Issue 4, April 2026.Dopaminergic neurons are particularly susceptible to ferroptosis. Pacemaking activity–driven calcium (Ca2+) influx increases metabolic demand and reactive oxygen species (ROS) production, promoting iron release from aconitase. Alpha‐synuclein (α‐syn) enhances iron uptake via transferrin receptor 1 (TfR1) and exhibits ferrireductase activity, converting
Carmem L. Sperlich +2 more
wiley +1 more source
The biosynthesis of riboflavin and related pteridines [PDF]
, 1961 The evidence in the literature relating to the biosynthesis of riboflavin and of other simpler pteridines is reviewed. Possible intermediates in the transformation of purines into pteridines are discussed and the chemistry of some of these compounds has ...
Neilson, Thomas
core
Chemistry – A European Journal, Volume 32, Issue 9, 2 March 2026.High‐energy proton irradiation of a formamide–diaminomaleonitrile–glycine system in the presence of meteorites produces a broad spectrum of biogenic compounds, including nucleobases, nucleosides, peptides, and nucleobase–peptide conjugates, highlighting a chemically plausible prebiotic network.
Bruno Mattia Bizzarri +6 more
wiley +1 more source
Normalization of Urinary Pteridines by Urine Specific Gravity for Early Cancer Detection
, 2014 Background: Urinary biomarkers, such as pteridines, require normalization with respect to an individual\u27s hydration status and time since last urination.
Shi, Honglan, Ma, Yinfa, Burton, Casey
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Archiv der Pharmazie, Volume 359, Issue 3, March 2026.In a series of substituted 1‐[5‐(5‐nitrofuran‐2‐yl)‐1,3,4‐thiadiazol‐2‐yl]piperidine‐4‐carboxamides evaluated for in vitro antileishmanial and antitrypanosomal activity, compound 18 emerged as the most promising derivative, showing submicromolar anti‐parasitic effects targeting diverse Leishmania and Trypanosoma species and acceptable selectivity ...
Alireza Mousavi +17 more
wiley +1 more source
Syntheses of highly functionalised 6-substituted pteridines
, 2003 Methods for the synthesis of polyfunctional 6-substituted pteridines from the corresponding 6-aldehydes are described. Alkene, ester, ketone, amide, cyano, oxime, bromo, methoxy and dihydroxy functional groups have all been introduced principally through
Guiney, D., Gibson, C.L., Suckling, C.J.
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A Modified Microbiological Method for Determination of Folate Levels in Erythrocyte and Plasma
Pteridines, 2007 Pteridines are natural heterocyclic compounds and they are generally divided into two main groups which are denominated as conjugated and unconjugated pteridines.
Sipahi Hande +3 more
doaj +1 more source
Chemical studies of 8-substituted pteridines [PDF]
, 1964 An account is given of the methods which are at present available for the aynthesis of 8-substituted pteridines and the closely allied 9-substituted isoalloxazine derivatives.
Rowan, Thomas
core
Journal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.ABSTRACT The correct diagnosis of tetrahydrobiopterin (BH4, sapropterin dihydrochloride)‐responsive phenylketonuria (PKU) and treatment with BH4 are important for prognosis and quality of life. We examined whether age affects biopterin bioavailability following oral BH4 administration in PKU and whether this influences BH4 responsiveness.
Kana Kitayama +5 more
wiley +1 more source
, 1991 Fuchs D, Krämer A, Reibnegger G, et al. Neopterin and [beta]2-microglobulin as prognostic indices in human immunodeficiency virus type 1 infection. Infection.
Werner, Ernst R. +6 more
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