Results 61 to 70 of about 3,953 (191)

Reconfiguring biofortification strategies to transform food systems and address micronutrient deficiency of the 21st century

Journal of Integrative Plant Biology, Volume 68, Issue 8, Page 2511-2547, August 2026.
This review explores how to make staple foods and horticultural crops more nutritious, including how artificial intelligence‐based screening of gene banks helps deploy nutritionally rich germplasm into breeding. Genome editing can help develop crops richer in minerals, vitamins, and health‐promoting compounds, supporting healthier diets and more ...
Rhowell Jr. N. Tiozon, Alisdair R. Fernie, Nese Sreenivasulu   +2 more
wiley   +1 more source

Release of Neopterin, PMN Elastase and Terminal Complement Complexes by Orthotopic Liver Transplantation with and without the Use of Veno-venous Bypass

Pteridines, 1998
Aim: The aim of the study was to determine whether orthotopic liver transplantation leads to the activation of macrophages, neutrophils and complement.
Tomasdottir H., Rønholm E., Bengtson JP, Bengtsson A.   +3 more
doaj   +1 more source

Photo-reduction of Pteridines [PDF]

Nature, 1956
WHEN a solution of 7-hydroxypteridine1 was spotted on a sheet of Whatman No. 1 filter paper, irradiated with ultra-violet light (principally 254 mµ) for 5 min., and developed (by ascending chromatography) in various solvents, two spots appeared. One of these was identical with the starting material (unirradiated material was used as a control on the ...
openaire   +2 more sources

Soluble Fas ligand and neopterin in patients with systemic and cutaneous discoid lupus erythematosus

Pteridines, 2000
Evidence accumulates suggesting that the pathogenesis in systemic lupus erythematosus (SLE) is associated with modulations in the Fas/FasL system. Serum concentrations of soluble Fas ligand (sFasL) were found to be elevated in patients with SLE.
Wirleitner Barbara, Kowald Elisabeth, Widner Bernhard, Ortner Ulrike, Baier-Bitterlich Gabriele, Sepp Norbert, Fuchs Dietmar   +6 more
doaj   +1 more source

Pteridines, LXXVII. C-Acylations of Pteridines by Homolytic Heteroaromatic Substitution [PDF]

, 1986
Homolytic substitution reactions with acyl radicals proceed with 2,4-diamino- (VI-VIlI) and 4-amino-2-methylthiopteridines (XXVII-XX IX) selectively at position 7 to give the corresponding 7-acyl derivatives IX-XV and XXX-XXXV, respectively, in moderate ...
Baur, Ralph, Ralph Baur, Boruah, Romeseh C., Wolfgang Pfleiderer, Pfleiderer, Wolfgang, Romeseh C. Boruah   +5 more
core   +1 more source

A Recessive oca2 Mutation Underlies Albinism in Xiphophorus Fish

Pigment Cell &Melanoma Research, Volume 39, Issue 4, July 2026.
Genetic mapping of albino Xiphophorus hellerii showed that albinism is associated with a recessive oca2 variant. This variant leads to early termination of the Oca2 protein. This study identifies a novel model system to investigate conserved mechanisms of pigmentation biology.
Yanting Xing, William Boswell, Jessica Parker, Kang Du, Manfred Schartl, Yuan Lu   +5 more
wiley   +1 more source

Role of Weak Molecular Interactions in the Mechanism of Action of a Series of Antihelmintics

Molecules, 2000
Different physicochemical properties such as solute-solute and solute-solvent interactions, tautomerism, lipophilicity and solubility in water were determined for a serie of 6,7-diaryl-pteridines in order to relate those properties with their nematocide ...
Marisa Santo, Liliana Giacomelli, Mario Reta, Rosa Cattana, Antonio Chana, Juana Silber, Carmen Ochoa, Mercedes Rodriguez   +7 more
doaj   +1 more source

Capture‐SELEX of DNA Aptamers for Highly Selective Binding of Folate

ChemBioChem, Volume 27, Issue 10, 27 May 2026.
Using capture‐SELEX, a DNA aptamer with sub‐micromolar affinity for folate was isolated, showing excellent selectivity. Using this aptamer, a light‐up fluorescent biosensor was developed for folate detection. Folate (vitamin B9) is an essential micronutrient for human health, particularly during pregnancy.
Yachen Xie, Yifan Chen, Juewen Liu
wiley   +1 more source

Novel Insights Into the Association Between Parkinson's Disease and Constipation: Role of SHMT2 as a Promising Biomarker

CNS Neuroscience &Therapeutics, Volume 32, Issue 5, May 2026.
This study integrated bioinformatics analysis, cellular models, and PD/constipation mouse models to identify SHMT2 as a key shared biomarker linking Parkinson's disease and constipation. SHMT2 upregulation was validated in dopaminergic neurons and the enteric nervous system, highlighting its potential role in gut–brain axis dysfunction.
Jiehua Su, Kaixun Huang, Xiuna Jing, Xiaohuan Liu, Cheng Wen, Rulin Geng, Zhuoying Lai, Zhijia Ruan, Yiqiang Zhan, Danyu Lin, Enxiang Tao   +10 more
wiley   +1 more source

Colour Morphs as Alternative Solutions to the Trade‐Off Predicted by the Immuno‐Competence Handicap Hypothesis

Integrative Zoology, Volume 21, Issue 3, Page 639-651, May 2026.
In this study, we tested whether white and yellow morphs of the common wall lizard (Podarcis muralis) adopt alternative strategies shaped by the immuno‐competence handicap hypotheses (ICHH). We found that testosterone‐induced immune suppression was stronger in white males, while aggression decreased in both morphs.
Roberto Sacchi, Alan J. Coladonato, Stefano Scali, Marco A. L. Zuffi, Rupert Palme, Marco Mangiacotti   +5 more
wiley   +1 more source