Results 71 to 80 of about 147,494 (267)

Changing Modalities

open access: yesJournal of Logic and Computation, 2004
The paper is devoted to an investigation of properties of dynamic modal logics with some interesting and rich features. A dynamic modal logic DML and its extension \(\mu\)DML are presented. They were developed in order to unify and extend dynamic epistemic logics proposed before in another paper by the author.
openaire   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Parametric Modal Study and Optimization of the Floor Pan of a B-Segment Automotive Using a Hybrid Method of Taguchi and a Newly Developed MCDM Model

open access: yesLatin American Journal of Solids and Structures
The floor pan is an important component that connects the front and rear segments of the automotive underbody structure. Global stiffness and NVH characteristics of BIW are highly dependent to shape, thickness and mass of the body panels and could be ...
Mohammad Hassan Shojaeefard   +2 more
doaj   +1 more source

Semantic and pragmatic values of the Italian imperfetto: Towards a common interpretive procedure

open access: yesCatalan Journal of Linguistics, 2015
This paper proposes an account of the semantics and pragmatics of the Italian indicative imperfect. This tense is described as deriving all of its uses from an extremely reduced core of semantic features as the point of departure to a series of ...
Laura Baranzini, Claudia Ricci
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

A Comparation Of Chinese And Indonesian Time Adverbs

open access: yesLingua Cultura, 2012
Chinese time adverbs describe status of behavior, modal frequency, or that the behavior has occurred, occurred in the past, present or future. When describe a time, it usually emphasizes the meaning. Indonesian time adverbs describe an event or action
Yi Ying
doaj  

Modals and Modality in English

open access: yesMiscelánea: A Journal of English and American Studies, 1995
Modality as a linguistic notion has a clear expression in English through the use of different modal verbs. In this respect, we can approach this fact from both a diachronic and a synchronic perspective. In the development of modals in time, it is interesting to consider Bernd Heine's account, for whom modals' development should be considered within a ...
openaire   +2 more sources

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