Results 91 to 100 of about 1,564,204 (345)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

IMPLIKASI PUNGUTAN OLEH OTORITAS JASA KEUANGAN TERHADAP KINERJA NOTARIS PEMEGANG SERTIFIKAT PASAR MODAL [PDF]

open access: yes, 2015
Notaris yang melakukan kegiatan dibidang pasar modal harus terlebih dahulu mengikuti pelatihan sertifikat pasar modal serta terdaftar di Otoritas Jasa Keuangan dengan persyaratan dan tata cara yang telah ditentukan, notaris yang telah terdaftar di ...
Virnabella, Ius Yosika
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Levels of Reality

open access: yesLanguages, 2019
Two fundamental aspects of conceptual and linguistic structure are examined in relation to one another: organization into strata, each a baseline giving rise to the next by elaboration; and the conceptions of reality implicated at successive levels of ...
Ronald W. Langacker
doaj   +1 more source

On modality in Georgian sign language (GESL) [PDF]

open access: yes, 2017
Modality is one of the most fascinating and complex areas of language studies. This paper illustrates the types of modal constructions in Georgian Sign language (GESL), including negative forms.
Makharoblidze, Tamar
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Vibration analysis of piping connected with shipboard equipment

open access: yesFrontiers in Mechanical Engineering
The piping system connected with the shipboard equipment may be subjected to excessive vibration due to harmonic base excitation produced by hydrodynamic force imposed on the propeller blades interacting with the hull and by other sources.
Radharaman Tripathi   +9 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

PENGELOLAAN WAKAF TUNAI

open access: yesWalisongo: Jurnal Penelitian Sosial Keagamaan, 2011
Basic issue on waqaf is the management, especially on the management of cash money. The institutions having in charge for managing the waqaf of cash money, have some management specific characteristics and patterns.
Muhyar Fanani
doaj   +1 more source

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