Results 81 to 90 of about 1,454,061 (346)

Relational Modality

open access: yesJournal of Logic, Language and Information, 2008
Saul Kripke's thesis that ordinary proper names are rigid designators is supported by widely shared intuitions about the occurrence of names in ordinary modal contexts. By those intuitions names are scopeless with respect to the modal expressions. That is, sentences in a pair like Aristotle might have been fond of dogs Concerning Aristotle, it is ...
Pagin, Peter, Glüer, Kathrin
openaire   +4 more sources

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

A comparison of modal flexibility method and modal curvature method in structural damage detection [PDF]

open access: yes, 2010
Vibration based damage detection techniques examines the changes in dynamic properties of a structure such as frequency, mode shape and damping to indicate the presence of damage.
Zaharudin, Noor Sabrina
core  

Diagnostic Modalities

open access: yesInternational Journal of Surgery, 2016
The incidental detection of small renal masses on imaging undertaken to evaluate unrelated symptoms or conditions is an increasingly common occurrence. Accurate imaging characterisation is fundamental to determining optimum patient management. The goals of imaging small renal masses include determining whether a lesion is solid or cystic, if there are ...
Alison, Elstob   +2 more
openaire   +2 more sources

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Research on Modal Enhancement of EMU Vehicle Carbody Structure Based on Sensitivity Analysis

open access: yesChengshi guidao jiaotong yanjiu
Objective To comprehensively understand the influence of carbody component dimensions on carbody modal characteristics, a sensitivity analysis of EMU (electric multiple units) body modal is conducted to enhance the main vibration frequency of carbody ...
DU Yanpin   +3 more
doaj   +1 more source

On modality in Georgian sign language (GESL) [PDF]

open access: yes, 2017
Modality is one of the most fascinating and complex areas of language studies. This paper illustrates the types of modal constructions in Georgian Sign language (GESL), including negative forms.
Makharoblidze, Tamar
core  

Changing Modalities

open access: yesJournal of Logic and Computation, 2004
The paper is devoted to an investigation of properties of dynamic modal logics with some interesting and rich features. A dynamic modal logic DML and its extension \(\mu\)DML are presented. They were developed in order to unify and extend dynamic epistemic logics proposed before in another paper by the author.
openaire   +3 more sources

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

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