Results 111 to 120 of about 831,882 (288)
Vibration signature analysis of multistage gear transmission [PDF]
An analysis is presented for multistage multimesh gear transmission systems. The analysis predicts the overall system dynamics and the transmissibility to the gear box or the enclosed structure.
Choy, F. K. +3 more
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Modal analysis of a 100449 tdw bulk carrier for the amidships cargo hold structure.
Annals of "Dunărea de Jos" University of Galaţi: Fascicle XI ShipbuildingA modal analysis of the ships’ structures is requested at any design step to check the possibility of local resonance occurring with onboard systems and equipment. The main study objective is to perform a local modal analysis of the amishships cargo hold
Elena Cristina Saltan +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Applied SciencesThe mode superposition method has been widely used for the seismic response analysis of two-dimensional (2D) sites to enhance computational efficiency. However, this method lacks a guideline of modal truncation to control errors of acceleration responses.
Hongkai Chen +3 more
doaj +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Modal Analysis and Test Research of Double Meshing Needle Teeth Cam Indexing Mechanism
Jixie chuandong, 2019 In order to explore the vibration characteristics of a new type of intermittent mechanism—double meshing needle teeth cam indexing mechanism，considering the complex connection relationship between various components， the finite element model of the ...
Mingtao Liu +4 more
doaj
Acoustical modal analysis of the pressure field in the tailpipe of a turbofan engine [PDF]
The results of a modal analysis of the pressure field in the tailpipe of a turbofan engine are presented. Modal amplitudes, at the tailpipe inlet and exit, are presented, as a function of frequency, for several operating conditions.
Karchmer, A. M., Krejsa, E. A.
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source