Results 111 to 120 of about 82,652 (246)

Operational modal analysis from flight test data

open access: yes, 2013
In the framework of the operational modal analysis (OMA), several approaches have been developed for estimating the modal parameters, i.e., natural frequencies, damping ratios, and mode shapes.
COPPOTELLI, Giuliano   +2 more
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Modal analysis of a 100449 tdw bulk carrier for the amidships cargo hold structure.

open access: yesAnnals of "Dunărea de Jos" University of Galaţi: Fascicle XI Shipbuilding
A modal analysis of the ships’ structures is requested at any design step to check the possibility of local resonance occurring with onboard systems and equipment. The main study objective is to perform a local modal analysis of the amishships cargo hold
Elena Cristina Saltan   +1 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

A Fast Method for the Acceleration Response Analysis of Two-Dimensional Sites Under Seismic Excitations

open access: yesApplied Sciences
The mode superposition method has been widely used for the seismic response analysis of two-dimensional (2D) sites to enhance computational efficiency. However, this method lacks a guideline of modal truncation to control errors of acceleration responses.
Hongkai Chen   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Using three-parameter sine fitting for scaling mode shapes with omah

open access: yes, 2017
Scaling mode shapes obtained by operational modal analysis (OMA) is sometimes desirable, for example if the modal model is going to be used for model calibration, or for some structural health monitoring applications. A new method for scaling mode shapes
Berardengo, M.   +6 more
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

From Input-Output to Output-Only Modal Identification of Civil Engineering Structures [PDF]

open access: yes, 2005
This paper presents a brief characterization of the evolution of Experimental Modal Analysis in the Civil Engineering field, from Input-Output to Output-Only Modal Identification Techniques, taking particularly into account the experience of the authors ...
Elsa Caetano, Álvaro Cunha
core  

Modal Analysis and Test Research of Double Meshing Needle Teeth Cam Indexing Mechanism

open access: yesJixie chuandong, 2019
In order to explore the vibration characteristics of a new type of intermittent mechanism—double meshing needle teeth cam indexing mechanism,considering the complex connection relationship between various components, the finite element model of the ...
Mingtao Liu   +4 more
doaj  

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