Results 121 to 130 of about 831,882 (288)
Assessing Modal Resonance in Power Systems Using Pseudo-Spectral Analysis
IEEE AccessIn this paper, a systematic methodology based on pseudo-spectral analysis is proposed to assess modal coalescence and the proximity to parametric resonance.
Erlan R. Murillo-Aguirre +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Analysis of Modal and Vibration Response of Gearbox of Urban Rail Train
Jixie chuandong, 2016 The gearbox is an important urban rail train transmission equipment. Aiming at the problem of the gearbox housing easily damaged caused by the vibration,by the Creo to create the three- dimensional modeling of box and transmission components,and then ...
Chen Zhongwei, 2Lu Ning, Yang Jianwei
doaj
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Development and correlation: Viking Orbiter analytical dynamic model with modal test [PDF]
The Viking Orbiter (VO) experience in the achievement of a mathematical model is described along with the following project activities: (1) the generation of the overall plan for load analysis, an analytical dynamic model, and development tests; (2) the ...
Chen, J. C., Garba, J. A., Wada, B. K.
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Effect of Boundary Conditions to Modal Parameters of Proportion Body
机车电传动, 2017 Boundary conditions are foundation of structural modal analysis. Different boundary conditions loading methods influence structural modal parameters via changing the structural stiffness.
SHI Yanmin +4 more
doaj
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source