HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Modal Analysis-Based Detection of Barely Visible Impact Damage in Carbon/Epoxy Overwraps of Type-IV Polymer-Lined Pressure Vessels. [PDF]
Bocian M +4 more
europepmc +1 more source
Automated Operational Modal Analysis for Rotating Machinery Based on Clustering Techniques. [PDF]
Dreher NR, Storti GC, Machado TH.
europepmc +1 more source
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Modal identification of machine tool spindle units by output only operational modal analysis. [PDF]
Chin P, Veldhuis SC.
europepmc +1 more source
Modal Analysis Using Digital Image Correlation Technique. [PDF]
Frankovský P +5 more
europepmc +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Jacobi-Ritz formulation for modal analysis of thick, anisotropic and non-uniform electric motor stator assemblies considering axisymmetric vibration modes. [PDF]
Andreou P +3 more
europepmc +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
The role of cellular heterogeneity in thyroid cancer: a multi-modal analysis approach with Mendelian randomization. [PDF]
Qian Y, Chen W, Chen X, Cheng S, Liu F.
europepmc +1 more source

