Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Identification of modal parameters for complex structures by experimental modal analysis approach
In this research, we have proposed a methodology for experimental identification of modal parameters based on measurement of the frequency responses of structures with complex geometries and performed an overall investigation of structural behavior on a ...
Tamara Nestorović +2 more
doaj +1 more source
Strain Modal Analysis of Small and Light Pipes Using Distributed Fibre Bragg Grating Sensors
Vibration fatigue failure is a critical problem of hydraulic pipes under severe working conditions. Strain modal testing of small and light pipes is a good option for dynamic characteristic evaluation, structural health monitoring and damage ...
Jun Huang +5 more
doaj +1 more source
Modal Analysis of Medium Calibre Barrels [PDF]
The paper deals with modal analysis of the two different medium calibre barrel weapons. At present time PC software which are based on FEM modal analysis enable not only create a new design but also check old design how be up to standard on the fire ...
Peter LISY, Lukáš BRIDIK
doaj +1 more source
Elucidating the Correlation between Bone Mineral Density and Multifidus Muscle Characteristics: A Cross-Modal Study with Dual-Energy X-ray Absorptiometry and Spinal Computed Tomography Texture Analysis [PDF]
Min-Woo Kim +4 more
openalex +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Overview of Air-Rail Passenger Transport Relationship from 1997 to 2018
World international passenger transport nowadays is dominated by air transport, while domestic passenger transport in certain region relies on rail transport.
Waralee Peetawan
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
A Study of Whole Joint Model Calibration Using Quasi-Static Modal Analysis [PDF]
David Najera-Flores, Robert J. Kuether
openalex +1 more source

