Results 61 to 70 of about 26,480,397 (286)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Operational modal analysis with non stationnary inputs [PDF]

open access: yes, 2013
Operational modal analysis (OMA) techniques enable the use of in-situ and uncontrolled vibrations to be used to lead modal analysis of structures. In reality operational vibrations are a combination of numerous excitations sources that are much more ...
Michon, Guilhem   +3 more
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Comparison of Different Independent Component Analysis Algorithms for Output-Only Modal Analysis

open access: yesShock and Vibration, 2016
From the principle of independent component analysis (ICA) and the uncertainty of amplitude, order, and number of source signals, this paper expounds the root reasons for modal energy uncertainty, identified order uncertainty, and modal missing in output-
Jianying Wang   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

On modal analysis of mechanical systems

open access: yesVietnam Journal of Mechanics, 1988
None
Nguyen Thac Si
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Operational modal Analysis of the “Guglia Maggiore” of the “Duomo” in Milano

open access: yes, 2011
Every city has its own symbol, its very heart. In Milano this symbol, with its six centuries of history, is the Duomo. One of the most impressive buildings in Italy, this unique Gothic cathedral continues to awe citizens and travelers with its timeless ...
VANALI, MARCELLO   +6 more
core  

Strain Modal Analysis of Small and Light Pipes Using Distributed Fibre Bragg Grating Sensors

open access: yesSensors, 2016
Vibration fatigue failure is a critical problem of hydraulic pipes under severe working conditions. Strain modal testing of small and light pipes is a good option for dynamic characteristic evaluation, structural health monitoring and damage ...
Jun Huang   +5 more
doaj   +1 more source

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