Results 71 to 80 of about 26,480,397 (286)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Experimental and operational modal analysis in support of modal model updating - a test case
, 2019 The introduction of new equipment on board of aircraft requires fatigue evaluations to determine maintenance intervals. This is particularly true when complex assemblies are required to be installed in aircraft areas exposed to combined stresses, most ...
Coppotelli Giuliano +1 more
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FINITE ELEMENT MODEL UPDATING OF A HISTORICAL MINARET VIA OPERATIONAL MODAL ANALYSIS [PDF]
, 2017 7th International Operational Modal Analysis Conference -- MAY 09-12, 2017 -- Ingolstadt, GERMANYFinite element method is commonly used for analysis of historical structures.
Hokelekli, E. +7 more
core +3 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Identification of the modal masses of an UAV structure in operational environment
, 2015 In the framework of Operational Modal Analysis, several methods have been developed to estimate the modal parameters, that is natural frequencies, damping ratios, and mode shapes of a structure in its operative conditions.
Arras, M. +2 more
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FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Operational modal testing of an arch type steel highway bridge using SSI technique
, 2011 4th International Operational Modal Analysis Conference, IOMAC 2011 -- 9 May 2011 through 11 May 2011 -- -- 110155The paper determines the dynamic characteristics of an arch type steel highway bridge applying ambient vibration testing.
Bayraktar, A. +2 more
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
, 2014 Tujuan dari penelitian ini adalah untuk mengetahui pengaruh perputaran modal kerja, struktur modal dan ukuran perusahaan terhadap profitabilitas pada perusahaan manufaktur yang terdaftar di Bursa Efek Indonesia pada tahun 2008-2011.
PENGARUH PERPUTARAN MODAL KERJA
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Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source