Low-authority control synthesis for large space structures [PDF]
The control of vibrations of large space structures by distributed sensors and actuators is studied. A procedure is developed for calculating the feedback loop gains required to achieve specified amounts of damping.
Aubrun, J. N., Margulies, G.
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Evaluation of Absolute Damping from Modal Damping Ratios
, 2018 Mario Paz, Young Hoon Kim
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Macrophage Extracellular Traps in Immunity and Cancer
Advanced Science, EarlyView.As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li +5 more
wiley +1 more source
Advanced Science, EarlyView.Schematic illustration of the synthesis protocol for Fe‐SH@Fn, an AML‐targeted nanoplatform engineered to co‐deliver shikonin (SH) and Fe3+, synergistically boosting antitumor immunity via ferroptosis induction and immunogenic cell death (ICD). ABSTRACT Acute myeloid leukemia (AML) remains a therapeutic challenge due to its low immunogenicity and ...
Shangqin Yang +9 more
wiley +1 more source
Integrated analysis and design of thick composite structures for optimal passive damping characteristics [PDF]
The development of novel composite mechanics for the analysis of damping in composite laminates and structures and the more significant results of this effort are summarized.
Saravanos, D. A.
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T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Machine learning-based Bayesian optimization of tuned inerter dampers for enhanced seismic response control in high-rise base-isolated structures. [PDF]
Sci RepHuang S, Zhu K.
europepmc +1 more source
Space shuttle active-pogo-suppressor control design using linear quadratic regulator techniques [PDF]
Two methods of active pogo suppression (stabilization) for the space shuttle vehicle were studied analytically. The basis for both approaches was the linear quadratic regulator, state space technique.
Lehtinen, B., Lorenz, C. F.
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Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis
Advanced Science, EarlyView.This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu +15 more
wiley +1 more source
An Enhanced Q-Factor Cantilever Resonator in Viscous Liquids Using Strategic Perforation. [PDF]
Micromachines (Basel)Qu S, Xia C.
europepmc +1 more source