Results 91 to 100 of about 2,942,391 (249)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Damage identification in a complex truss structure using modal characteristics correlation method and sensitivity-weighted search space [PDF]

open access: yes, 2019
Damage identification for complex structures is a challenging task due to large amount of structural elements, limited number of measured modes and uncertainties in referenced numerical models.
Nguyen, Andy   +3 more
core   +1 more source

Target-Free Stereo-Vision-Based Modal Identification of a Cantilever Beam Using Physics-Aware Deep-Feature Tracking

open access: yesInfrastructures
Reliable target-free vision-based modal identification remains challenging because accurate image correspondence does not necessarily guarantee physically reliable structural measurements.
Sherbaz Khan   +3 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Modal identification and stiffness degradation of concrete block masonry buildings [PDF]

open access: yes, 2013
A new construction system for masonry buildings is analysed. Identification of modal parameters has been carried out in two structural solutions by using this system namely reinforced and unreinforced symmetric two-story concrete block masonry buildings.
Lourenço, Paulo B.   +3 more
core   +2 more sources

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Monitoring the effects of impact damages on modal parameters in carbon fiber entangled sandwich beams [PDF]

open access: yes, 2009
The aim is to study the impact toughness of two types of entangled sandwich materials (heavy and light) with the help of vibration testing. A simple case of symmetrical impacts is studied in this article as no literature is available regarding impact ...
Bouvet, Christophe   +4 more
core   +1 more source

Consistent cross-modal identification of cortical neurons with coupled autoencoders. [PDF]

open access: yesNat Comput Sci, 2021
Gala R   +10 more
europepmc   +1 more source

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