Results 41 to 50 of about 1,916,405 (251)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Parameter identification and hybrid mathematical modelling techniques applied to non-linear control systems [PDF]

The study is concerned with the mathematical modelling and parameter identification of nonlinear motion control systems. The control systems under review are the axis motion control systems for a 3-axis CNC machine tool.
Pislaru, Crinela
core   +4 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Modal Logics are Coalgebraic [PDF]

, 2008
Applications of modal logics are abundant in computer science, and a large number of structurally different modal logics have been successfully employed in a diverse spectrum of application contexts.
Pattinson, Dirk, Schröder, Lutz, Cirstea, Corina, Kurz, Alexander, Venema, Yde   +4 more
core   +2 more sources

Dynamic Parameter Identification of Hydrodynamic Bearing-Rotor System

Shock and Vibration, 2015
A new method called modal parameter genetic time domain identification was employed to study the characteristics of the bearing-rotor system. A multifrequency signal decomposition technology to identify the main components of the measured signal and ...
Zhiqiang Song, Yunhe Liu
doaj   +1 more source

Short-Term Wind Speed Forecasting Based on the EEMD-GS-GRU Model

Atmosphere, 2023
To improve the accuracy of short-term wind speed forecasting, we proposed a Gated Recurrent Unit network forecasting method, based on ensemble empirical mode decomposition and a Grid Search Cross Validation parameter optimization algorithm. In this study,
Huaming Yao, Yongjie Tan, Jiachen Hou, Yaru Liu, Xin Zhao, Xianxun Wang   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Dynamic Testing and Finite Element Model Adjustment of the Ancient Wooden Structure Under Traffic Excitation

Buildings
In situ dynamic testing is conducted to study the dynamic characteristics of the wooden structure of the North House main hall. The velocity response signals on the measurement points are obtained and analyzed using the self-interaction spectral method ...
Xin Wang, Zhaobo Meng, Xiangming Lv, Guoqiang Wei   +3 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source