Results 91 to 100 of about 4,345,353 (297)
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
New Trends in Parameter Identification for Mathematical Models
, 2018 The Proceedings volume contains 16 contributions to the IMPA conference “New Trends in Parameter Identification for Mathematical Models”, Rio de Janeiro, Oct 30 – Nov 3, 2017, integrating the “Chemnitz Symposium on Inverse Problems on Tour”.
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Hysteretic Characteristics of Wood-Frame Structures Under Seismic Motions [PDF]
, 2009 In order to develop seismic codes that can effectively mitigate damage to wood-frame construction under seismic activity, the dynamic characteristics of wood-frame buildings must be well understood.
Sutoyo, Daniel
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SensorsModal parameter estimation is crucial in vibration-based damage detection and deserves increased attention and investigation. Concrete arch dams are prone to damage during severe seismic events, leading to alterations in their structural dynamic ...
Xinyi Zhu +8 more
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Parameter identification using modal data [PDF]
, 1988 Parameter identification using experimental modal data is examined. The following approaches are discussed: (1) Direct - using actual sensor measurements to obtain parameters (e.g., ERA, ITD); and (2) Indirect - identifies parameters using measured modal
Meirovitch, L., Norris, M. A.
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Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
System identification and structural health monitoring of bridge structures [PDF]
, 2013 This research study addresses two issues for the identification of structural characteristics of civil infrastructure systems. The first one is related to the problem of dynamic system identification, by means of experimental and operational modal ...
Islami, Kleidi
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On the Accuracy of the Modal Parameter Estimates in OMA
, 2023 Modal identification procedures are used to evaluate the vibration properties of structures and can be divided into two branches, that is Input-Output and Output-Only analyses.
Paulsen, Thomas Thougaard +2 more
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