Results 91 to 100 of about 18,619 (308)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Research of the Operational Modal Parameter Identification Technology and Application based on QICA

open access: yesJixie chuandong, 2015
Aiming at the major difficulties of OMA method based on vibration signals such as low noise-robust ability,high subjective experience and poor accuracy in identifying parameters and more complex recognition method,a new method of OMA on the basis of QICA
Zhang Rui   +5 more
doaj  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

MEMS-Based Vibration Acquisition for Modal Parameter Identification of Substation Frame

open access: yesApplied Sciences
As a critical component of substations, the substation frames are characterized by significant height and span, which presents substantial challenges and risks in conducting dynamic response tests using traditional sensors. To simplify these difficulties,
Ruochen Qiang   +5 more
doaj   +1 more source

Intelligent Modal Analysis System: Autonomous Identification and Tracking of Aircraft Modal Parameters [PDF]

open access: yes
Efficient aircraft design necessitates lightweight constructions. However, this leads to aeroelastic challenges concerning loads and vibrations. One example is an unstable, self-excited vibration called flutter, which can result in structural failure. Flutter results from a coupling of one or more structural dynamic modes of the aircraft structure and ...
openaire   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Ambient vibration testing of concrete dams

open access: yes, 2011
In this thesis, seven techniques namely; rational fractional polynomial, complex exponential, frequency domain decomposition (FDD) based techniques which include; frequency domain decomposition (FDD), enhanced frequency domain decomposition (EFDD), curve
Bukenya, Patrick
core  

Damage identification in a concrete beam using curvature difference ratio

open access: yes, 2011
Previous studies utilising changes in mode shape or curvature to locate damage rely on the fact that the greatest change occurs around the defect. However, in concrete beams this fact is undermined due to the nature of the defect as distributed multi ...
Mohammad, FA   +7 more
core   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

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