Results 81 to 90 of about 474,164 (345)

Temperature-dependent thermo-elastic parameter identification for composites using thermal modal data

open access: yesAdvances in Mechanical Engineering, 2019
To accurately determine the temperature-dependent parameters of composites, a thermo-elastic parameter identification approach using thermal modal data is proposed in this article.
Dong Jiang   +3 more
doaj   +1 more source

On-Line Modal Parameter Identification Applied to Linear and Nonlinear Vibration Absorbers

open access: yesActuators, 2020
A solution of the vibration attention problem on a flexible structure from a dynamic vibration absorption perspective is experimentally and numerically studied in this article.
Luis Gerardo Trujillo-Franco   +4 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Output-Only Modal Parameter Recursive Estimation of Time-Varying Structures via a Kernel Ridge Regression FS-TARMA Approach

open access: yesShock and Vibration, 2017
Modal parameter estimation plays an important role in vibration-based damage detection and is worth more attention and investigation, as changes in modal parameters are usually being used as damage indicators.
Zhi-Sai Ma, Li Liu, Si-Da Zhou, Lei Yu
doaj   +1 more source

Automated Modal Parameters Identification During Ice-Structure Interactions

open access: yesVolume 2: Structures, Safety, and Reliability, 2022
Abstract Offshore structures are prone to damage caused by ice-induced vibrations. It is presently unknown to what extent different ice conditions change the properties of the structure, such as natural frequency, damping ratio, and mode shape.
Wang, Chunlin   +2 more
openaire   +2 more sources

Dynamics of mistuned radial turbine wheels [PDF]

open access: yes, 2006
This paper presents investigations carried out at Holset into the dynamics of mistuned radial turbine wheels, including a literature review, a lumped parameter model, identification of the most responsive blade, distribution of the peak maximum order ...
Bendiksen   +17 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Dynamic investigation on the Mirandola bell tower in post-earthquake scenarios [PDF]

open access: yes, 2016
After the seismic events of the 20th and 29th of May 2012 in Emilia (Italy), most of the monumental and historic buildings of the area were severely damaged. In a few structures, partial collapse mechanisms were observed (e.g.
Boscato, Giosue   +6 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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