Results 61 to 70 of about 18,619 (308)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Advances in Mechanical Engineering, 2019 To accurately determine the temperature-dependent parameters of composites, a thermo-elastic parameter identification approach using thermal modal data is proposed in this article.
Dong Jiang +3 more
doaj +1 more source
On-Line Modal Parameter Identification Applied to Linear and Nonlinear Vibration Absorbers
Actuators, 2020 A solution of the vibration attention problem on a flexible structure from a dynamic vibration absorption perspective is experimentally and numerically studied in this article.
Luis Gerardo Trujillo-Franco +4 more
doaj +1 more source
On the Accuracy of the Modal Parameter Estimates in OMA
, 2023 Modal identification procedures are used to evaluate the vibration properties of structures and can be divided into two branches, that is Input-Output and Output-Only analyses.
Paulsen, Thomas Thougaard +2 more
core
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Shock and Vibration, 2017 Modal parameter estimation plays an important role in vibration-based damage detection and is worth more attention and investigation, as changes in modal parameters are usually being used as damage indicators.
Zhi-Sai Ma, Li Liu, Si-Da Zhou, Lei Yu
doaj +1 more source
Modal parameter identification based on ARMAV and state–space approaches
, 2010 International audienceAn accurate prediction for the response of civil and mechanical engineering structures subject to ambient excitation requires the information of dynamic properties of these structures including natural frequencies, damping ratios ...
Lardies, Joseph
core +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Comparação de métodos de determinação do amortecimento estrutural através de técnicas de ajuste de curvas de funções resposta em frequência [PDF]
, 2013 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológio. Programa de Pós-Graduação em Engenharia Mecânica, Florianópolis, 2013A fenomenologia complexa dos mecanismos de amortecimento dos materiais e das estruturas impede a ...
Masotti, Diego
core
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source