Results 51 to 60 of about 4,345,353 (297)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

On the robustness of the average power ratios in damping estimation: application in the structural health monitoring of composites beams [PDF]

open access: yes, 2010
In composites structures, cracking, delamination will cause changes in the measured dynamic response of structure and so on experimentally modal parameters.
J. Morlier   +4 more
core   +1 more source

A New Maximum Likelihood Estimator Formulated in Pole-Residue Modal Model

open access: yesApplied Sciences, 2019
Recently, a lot of efforts have been devoted to developing more precise Modal Parameter Estimation (MPE) techniques. This is explained by the necessity in civil, mechanical and aerospace engineering of obtaining accurate estimates for the modal ...
Sandro Amador   +3 more
doaj   +1 more source

Identification of modal parameters using the wavelet transform

open access: yesInternational Journal of Mechanical Sciences, 2002
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Lardies, Joseph, Gouttebroze, Stéphane
openaire   +2 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Temperature-dependent thermo-elastic parameter identification for composites using thermal modal data

open access: yesAdvances in Mechanical Engineering, 2019
To accurately determine the temperature-dependent parameters of composites, a thermo-elastic parameter identification approach using thermal modal data is proposed in this article.
Dong Jiang   +3 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Significance of low energy impact damage on modal parameters of composite beams by design of experiments [PDF]

open access: yes, 2009
This paper presents an experimental study on the effects of multi-site damage on the vibration response of composite beams damaged by low energy impacts around the barely visible impact damage limit (BVID).
A Shahdin   +6 more
core   +1 more source

On-Line Modal Parameter Identification Applied to Linear and Nonlinear Vibration Absorbers

open access: yesActuators, 2020
A solution of the vibration attention problem on a flexible structure from a dynamic vibration absorption perspective is experimentally and numerically studied in this article.
Luis Gerardo Trujillo-Franco   +4 more
doaj   +1 more source

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