Results 91 to 100 of about 18,357 (296)

Reliability-based Design Optimization of Complex Structures [PDF]

open access: yesE3S Web of Conferences
The purpose research over the last three decades has focused on the the “optimum” structural mechanics system. The Reliability-Based Design Optimization (RBDO) seeks to find the best compromise between safety and cost levels.
El Hami Abdelkhalak   +2 more
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Torsional vibration analysis of automotive drivelines [PDF]

open access: yes, 1997
One of the most important source of noise and vibrations associated with vehicles is the vibration of driveline systems. Such phenomena are subjectively associated with customer complaints.
Rabeih, El-Adl Mohammed Aly
core  

Application of System-level Analysis Method in Fan-driven Gearbox Test

open access: yesJixie chuandong, 2021
The fan-driven gearbox is characterized by complex structure and difficult system dynamics analysis. The accuracy of the component level model is verified through the modal analysis and the percussion modal test of the gearbox component.
Lü Zuopeng   +4 more
doaj  

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Accuracy of results with NASTRAN modal synthesis

open access: yes, 1978
A new method for component mode synthesis was developed for installation in NASTRAN level 17.5. Results obtained from the new method are presented, and these results are compared with existing modal synthesis ...
Herting, D. N.
core  

Understanding friction induced damping in bolted assemblies through explicit transient simulation [PDF]

open access: yes, 2014
The design of joints is seeing increased interest as one of the ways of controlling damping levels in lighter and more flexible aeronautic structures. Damping induced by joint dissipation has been studied for more than a decade, mostly experimentally due ...
VERMOT DES ROCHES, Guillaume   +1 more
core  

Mistuning Identification and Model Updating of an Industrial Blisk

open access: yesInternational Journal of Rotating Machinery, 2007
The results of a complete study of mistuning identification on an industrial blisk are presented. The identification method used here is based on a model-updating technique of a reduced order.
D. Laxalde   +4 more
doaj   +1 more source

Application of Free Interface Modal Synthesis Method on Modal Test Boundary Transformation of One Missile Wing

open access: yesDEStech Transactions on Engineering and Technology Research, 2017
The large deviation between test results and real conditions caused by the coupling of test fixture is unavoidable. The research on free interface modal synthesis method can gain the modal test boundary transformation of one missile wing. For this purpose, the low order normal mode spectrum matrix and mode shapes was gained by free modal test, the ...
Song FENG, Yun HE, Yan WEN
openaire   +2 more sources

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