Results 91 to 100 of about 741,275 (315)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

3D ultrasound guidance for radiofrequency ablation in an anthropomorphic thyroid nodule phantom

open access: yesEuropean Radiology Experimental
Background The use of two-dimensional (2D) ultrasound for guiding radiofrequency ablation (RFA) of benign thyroid nodules presents limitations, including the inability to monitor the entire treatment volume and operator dependency in electrode ...
Tim Boers   +4 more
doaj   +1 more source

The Semantics and Pragmatics of Deontic MUST, HAVE TO, and HAVE GOT TO [PDF]

open access: yes, 1999
Modality, which is deeply related with the mental state of human beings, has long been an important theme of linguistics, philosophy, psychology, etc. Since we cannot represent the situation without expressing our mental attitude towards it, we examine ...
高司, 正夫   +6 more
core  

Modality in Climate Change-Related Discourse by King Charles III [PDF]

open access: yes
The article presents a corpus-based study that aims at establishing how modality is used in climate change-related discourse by King Charles III of the United Kingdom of Great Britain and Northern Ireland (the UK). The study involved a corpus of speeches
Kapranov, Oleksandr, Oleksandr Kapranov
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Investigating the Semantic Development of Modal Markers: The Role of Context

open access: yesClotho, 2019
The article tackles the problem of studying diachronic semantic changes of modal markers in Latin. It proposes to do so by using context as a proxy for tracing the development of otherwise unchanging forms.
Tomaž Potočnik, Matej Hriberšek
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Examining factors that affect performance in complex simulation environments [PDF]

open access: yes, 2009
textThis study examined the effects of manipulating the modality (text-only, voice-only, voice+text) of a tutorial and restriction (restricted vs. unrestricted) of a simulation's interface on retention and transfer of tutorial content.
Mayrath, Michael Charles
core  

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye   +11 more
wiley   +1 more source

Proof of concept 3D ultrasound strain imaging measuring effect of a ring pessary on avulsed puborectal muscle

open access: yesCommunications Medicine
Background Placement or fitting of a ring pessary is one of the treatment options for women with pelvic organ prolapse (POP), resulting from avulsion. To determine the effect of ring pessary use in these women, usually qualitative measures like a patient
Shreya Das   +5 more
doaj   +1 more source

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