Results 81 to 90 of about 1,216,020 (296)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

JAVANESE LANGUAGE MODALITY IN BLENCONG ARTICLES OF SUARA MERDEKA NEWSPAPER [PDF]

, 2011
Many languages have modalities which are usually expressed through certain modal verbs. By analyzing the modal verbs, the varying degrees of commitment to or belief in a proposition can be explained. Javanese language also has such modal system.
Nina , Setyaningsih
core  

Digital task management platform enhances student academic achievement in economic development education

Discover Education
Based on self-regulated learning theory, a study at Universidad del Norte examined Trello's impact on student performance in an undergraduate Economic Development course. The quasi-experimental research involved 103 students across two semesters, with 52
Heidy Rico Fontalvo, Florentino Rico, Mario de la Puente, Tatiana Londoño, Daniela Navarro   +4 more
doaj   +1 more source

Impact of Injection Technique on Microsphere Distribution During Transarterial Radioembolization in a Successively Bifurcating In Vitro Model

Advances in Radiation Oncology
Purpose: This study aimed to experimentally investigate how injection technique affects the distribution of microspheres during transarterial radioembolization in a successively bifurcating in vitro model.
Tess J. Snoeijink, MSc, Jan L. van der Hoek, MSc, Anne van den Brekel, MSc, Gerhard van Wolfswinkel, MSc, Marcel J.R. Janssen, MD, PhD, Erik Groot Jebbink, PhD, J. Frank W. Nijsen, PhD   +6 more
doaj   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Phenomenological Actualism. A Husserlian Metaphysics of Modality? [PDF]

, 2014
Considering the importance of possible-world semantics for modal logic and for current debates in the philosophy of modality, a phenomenologist may want to ask whether it makes sense to speak of “possible worlds” in phenomenology.
Wallner, Michael
core  

3D ultrasound guidance for radiofrequency ablation in an anthropomorphic thyroid nodule phantom

European Radiology Experimental
Background The use of two-dimensional (2D) ultrasound for guiding radiofrequency ablation (RFA) of benign thyroid nodules presents limitations, including the inability to monitor the entire treatment volume and operator dependency in electrode ...
Tim Boers, Sicco J. Braak, Wyger M. Brink, Michel Versluis, Srirang Manohar   +4 more
doaj   +1 more source