Results 61 to 70 of about 1,216,020 (296)

Modal Expansionism [PDF]

Journal of Philosophical Logic, 2019
There are various well-known paradoxes of modal recombination. This paper offers a solution to a variety of such paradoxes in the form of a new conception of metaphysical modality. On the proposed conception, metaphysical modality exhibits a type of indefinite extensibility.
openaire   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Selective agonists of KIR and NKG2A to evade missing self response of natural killer cells

Scientific Reports
Immune rejection is one of the most serious challenges in allogeneic transplantation, including allogeneic induced pluripotent stem cell (allo-iPSC)-derived cell therapy. Beta-2-Microglobulin gene-knockout, human leukocyte antigen (HLA) class I-deficient
Satoshi Hiura, Yuto Kuwasaki, Yosuke Nishikawa, Takako Kimura, Sayaka Yoshida, Makiko Nakayama, Tomohiro Makino, Suguru Ueno   +7 more
doaj   +1 more source

Deep learning-based segmentation of 3D ultrasound images of the thyroid

WFUMB Ultrasound Open
The goal of the study was to develop a method for segmentation of the thyroid, carotid artery (CA), and jugular vein (JV) using 3D ultrasound data. This method forms the basis for a computer-assisted needle-based intervention for thyroid nodules and ...
Roxane Munsterman, Tim Boers, Sicco J. Braak, Jelmer M. Wolterink, Michel Versluis, Srirang Manohar   +5 more
doaj   +1 more source

Sequence-of-tense and the features of finite tenses

Nordlyd: Tromsø University Working Papers on Language & Linguistics, 2015
Sequence-of-tense (SOT) is often described as a (past) tense verb form that does not correspond to a semantically interpretable tense. Since SOT clauses behave in other respects like finite clauses, the question arises as to whether the syntactic ...
Karen Zagona
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Semi-supervised Deep Generative Modelling of Incomplete Multi-Modality Emotional Data

, 2018
There are threefold challenges in emotion recognition. First, it is difficult to recognize human's emotional states only considering a single modality. Second, it is expensive to manually annotate the emotional data.
Du, Changde, Du, Changying, He, Huiguang, Li, Jinpeng, Lu, Bao-Liang, Wang, Hao, Zheng, Wei-Long   +6 more
core   +1 more source

Effectiveness of a structured emotional literacy and stress management program for female heads of household: a two-year longitudinal study in Cartagena, Colombia, and Valencia, Venezuela

Critical Public Health
Female heads of household face unique stressors related to economic survival and family care, yet few evidence-based interventions address their specific emotional health needs.
Heidy Rico, Mario de la Puente, Florentino Rico, Tatiana Londoño   +3 more
doaj   +1 more source

Changing Modalities

Journal of Logic and Computation, 2004
The paper is devoted to an investigation of properties of dynamic modal logics with some interesting and rich features. A dynamic modal logic DML and its extension \(\mu\)DML are presented. They were developed in order to unify and extend dynamic epistemic logics proposed before in another paper by the author.
openaire   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source