Results 71 to 80 of about 1,216,020 (296)

Super phantoms: advanced models for testing medical imaging technologies

open access: yesCommunications Engineering
Phantoms are test objects used for initial testing and optimization of medical imaging techniques, but these rarely capture the complex properties of the tissue.
Srirang Manohar   +4 more
doaj   +1 more source

Multimodal integration of spatial information: The influence of object-related factors and self-reported strategies

open access: yesFrontiers in Psychology, 2016
Spatial representations are a result of multisensory information integration. More recent findings suggest that the multisensory information processing of a scene can be facilitated when paired with a semantically congruent auditory signal.
Harun Karimpur, Kai Hamburger
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Feasibility of Laser Speckle-Based Perfusion Imaging in an Ex-Vivo Liver Model

open access: yesIEEE Journal of Translational Engineering in Health and Medicine
Objective: Advancing microcirculatory perfusion assessment methods is crucial for evaluating organ status during ex-vivo organ preservation and expanding the donor pool.
Ata Chizari   +10 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Contingent Existence and the Reduction of Modality to Essence [PDF]

open access: yes, 2019
This paper first argues that we can bring out a tension between the following three popular doctrines: (i) the canonical reduction of metaphysical modality to essence, due to Fine, (ii) contingentism, which says that possibly something could have failed ...
Teitel, Trevor
core  

Modes on the Move: Interval Cycles and the Emergence of Major-Minor Tonality

open access: yesEmpirical Musicology Review, 2011
The issue of the emergence of major-minor tonality is addressed by recourse to a novel pitch grouping process, referred to as interval cycle proximity (ICP).
Matthew Woolhouse
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

What the Future ‘Might’ Brings [PDF]

open access: yes, 2020
This paper concerns a puzzle about the interaction of epistemic modals and future tense. In cases of predictable forgetfulness, speakers cannot describe their future states of mind with epistemic modals under future tense, but promising theories of ...
Boylan, David
core  

MODAL: A multilingual corpus annotated for modality [PDF]

open access: yes, 2017
We have produced a corpus annotated for modality which amounts to approximately 20,000 words in English, French, and Italian. The annotation scheme is based on the notion of epistemic construction and virtually languageindependent. The annotation is rigorously evaluated by means of a newly developed strategy based on the alignment of the entire ...
Nissim, Malvina, Pietrandrea, Paola
openaire   +3 more sources

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