Results 71 to 80 of about 340,881 (244)
Journal of Philosophical Logic, 2019 There are various well-known paradoxes of modal recombination. This paper offers a solution to a variety of such paradoxes in the form of a new conception of metaphysical modality. On the proposed conception, metaphysical modality exhibits a type of indefinite extensibility.
openaire +3 more sources
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Super phantoms: advanced models for testing medical imaging technologies
Communications EngineeringPhantoms are test objects used for initial testing and optimization of medical imaging techniques, but these rarely capture the complex properties of the tissue.
Srirang Manohar +4 more
doaj +1 more source
Feasibility of Laser Speckle-Based Perfusion Imaging in an Ex-Vivo Liver Model
IEEE Journal of Translational Engineering in Health and MedicineObjective: Advancing microcirculatory perfusion assessment methods is crucial for evaluating organ status during ex-vivo organ preservation and expanding the donor pool.
Ata Chizari +10 more
doaj +1 more source
Modes on the Move: Interval Cycles and the Emergence of Major-Minor Tonality
Empirical Musicology Review, 2011 The issue of the emergence of major-minor tonality is addressed by recourse to a novel pitch grouping process, referred to as interval cycle proximity (ICP).
Matthew Woolhouse
doaj +1 more source
FEBS Letters, EarlyView.Which brain hemisphere controls writing? This review synthesizes all five functional transcranial Doppler studies of writing (handwriting and typing) published to date in adults and children. Right‐handers show left‐hemispheric dominance for the linguistic component of writing (written word generation), whereas findings for left‐handers remain ...
Marietta Papadatou‐Pastou
wiley +1 more source
Conditional Sentences: ELT typology and corpus evidence. [PDF]
, 2003 This paper presents the findings of a pilot study examining the representation of the typology of conditional sentences presented in English language teaching (ELT) materials (coursebooks and grammars) in a random sample of 1,000 conditional sentences ...
Gabrielatos, Costas
core +3 more sources
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Frontiers in Psychology, 2013 Theories of embodied cognition (e.g., Perceptual Symbol Systems Theory; Barsalou, 1999, 2009) suggest that modality-specific simulations underlie the representation of concepts.
Lea eHald +6 more
doaj +1 more source