Results 131 to 140 of about 8,098,138 (300)
Türk halk müziğinin en önemli problemlerinden birisi terminolojidir. Bu problemlerin başında ise, Türk Halk Müziğinin melodik veya ezgisel yapısının adlandırılması konusu gelmektedir.
Savaş Ekici
doaj
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Rethinking context: realisation, instantiation, and individuation in systemic functional linguistics
In spite of decades of research developing a model of language and context, there is little consensus in systemic functional linguistics (SFL) about how context should be modelled and how language and context are related.
Doran Y. J. +2 more
doaj +1 more source
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Astrid Opitz, Modus in den Chansons von Binchois (= Saarbrücker Studien zur Musikwissenschaft, Bd. 18), Sinzig: Studio 2015 [PDF]
Carlo Bosi
doaj +1 more source
La mode française sous l’occupation allemande dans le journal d’Andrzej Bobkowski 1940 –1944
Bloqué à Paris en 1939 en route vers l’Amérique du Sud, Andrzej Bobkowski (1913–1961), écrivain et essayiste polonais, tient un journal intime durant la période de l’occupation allemande.
Krzysztof Trojanowski
doaj
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source

