Results 131 to 140 of about 7,171,930 (396)

A systematic review of machine learning classification methodologies for modelling passenger mode choice

open access: yesJournal of Choice Modeling, 2021
Tim Hillel   +3 more
semanticscholar   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Public Transport Accessibility and Its Effect on Mode Choice

open access: yesUrban Science
The relationship between the service of public transport (PT) and its use is complex but can be simplified through the use of indicators. These indicators should be able to accurately reflect PT use so that improvements in the indicators lead to ...
Fabian Kühnel   +3 more
doaj   +1 more source

Influencing Mechanism Analysis of Urban Form on Travel Energy Consumption—Evidence from Fukuoka City, Japan

open access: yesUrban Science, 2018
The increasing threat of transportation energy insecurity, environmental issues and public health issues have led to a growing body of research that looks at the potential contribution of urban planning in reducing travel energy consumption.
Sarita Maharjan   +2 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Modeling Travel Mode Choices in Connection to Metro Stations by Mixed Logit Models: A Case Study in Nanjing, China

open access: yesPromet (Zagreb), 2018
Urban rail transit trips usually involve multiple stages, which can be differentiated in terms of transfers that may involve distinct access and egress modes.
Jingxian Wu   +3 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

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