Results 141 to 150 of about 4,119,438 (303)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Car Ownership and Mode of Transport to Work in Ireland [PDF]

open access: yes
Rapid economic and demographic change in Ireland over the last decade, with associated increases in car dependence and congestion, has focused policy on encouraging more sustainable forms of travel.
Anne Nolan, Nicola Commins
core  

Effect of attribute perceptions on mode choice behavior in a transit market.

open access: yes, 2005
Random utility models are often used to model traveler mode choice behavior in the demand analysis of a transit system. Transit operators might base their policy and operations planning on these estimates.
Lo, Hong K, Wan, Quentin
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Exploring the impact of COVID-19 on individual's travel mode choice in China. [PDF]

open access: yesTransp Policy (Oxf), 2021
Luan S, Yang Q, Jiang Z, Wang W.
europepmc   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

CALIBRATING THE INTERCITY HIGH SPEED RAIL (HSR) CHOICE MODEL FOR THE RICHMOND-WASHINGTON, D.C. CORRIDOR [PDF]

open access: yes
This study aims to quantitatively investigate how the introduction of high-speed rail (HSR) influences traveler’s choice behavior. The study focuses on recalibrating the Florida-based HSR choice model to fit the intercity travel northward from Richmond ...
Xueming CHEN
core  

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