Results 131 to 140 of about 4,119,438 (303)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Inertia and shock effects on mode choice panel data: implications of the Transantiago implementation [PDF]

open access: yes, 2009
The mode choice process, especially in the case of commuter trips, reflects the strong tendency people have to simplify the assessment of their options when confronted with successive well-known decisions.
Heydecker, B.G.   +3 more
core  

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Passengers' Airport Choice [PDF]

open access: yes
Modelling airport choice of passengers has been a subject of interest for air transport scientists and airport managers already for a while. Wilken, Berster and Gelhausen have reported of a market segment specific model approach to airport choice in ...
Gelhausen, Marc Christopher
core  

Investigating Willingness to Shift to Formal Sustainable Public Transportation in Developing Cities: A Correlated Random Parameters Bivariate Probit Model

open access: yesFuture Transportation
Informal public transportation remains the backbone of urban mobility in many developing cities. While these systems offer flexible and affordable services, they are often associated with safety issues, unreliability, congestion, and environmental ...
Ziyad Shahin   +2 more
doaj   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

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