Results 121 to 130 of about 4,119,438 (303)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
, 2014 This study is part of the ‘Tailored Implementation for Chronic Diseases’ (TICD) project and is integrated in a program evaluation which has been designed as a two arm randomized controlled trial (NTR4069).
Wensing, Prof. Dr. M.J.P. (Radboud Universitair Medisch Centrum Nijmegen, IQ healthcare) DAI=info:eu-repo/dai/nl/089800761 +2 more
core +1 more source
Urban ScienceAir pollution poses growing challenges to public health and urban mobility in Southeast Asia. This study investigates how air quality crises affect travel mode choices in Chiang Rai, Thailand, a secondary city experiencing seasonal PM2.5 smog episodes. A
Ramill Phopluechai +5 more
doaj +1 more source
MODE CHOICE MODELLING OF PARATRANSIT MODES IN TRINIDAD [PDF]
Proceedings of the International Conference on Emerging Trends in Engineering & Technology (IConETech-2020), 2020 Leah Wright, Trevor Townsend
openaire +1 more source
Impact of COVID-19 on mode choice behavior: A case study for Dhaka, Bangladesh. [PDF]
Transp Res Interdiscip Perspect, 2022 Paul T +3 more
europepmc +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Exploring the Relationship between Built Environment and Commuting Mode Choice: Longitudinal Evidence from China. [PDF]
Int J Environ Res Public Health, 2022 Yin C, Wang X, Shao C, Ma J.
europepmc +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Modeling Limited-Stop Bus Corridor Services with Fare Payment Mode Choice and Trip Purpose Consideration. [PDF]
Comput Intell Neurosci, 2022 Tang C, Ge YE, Zhang J, Xu Q.
europepmc +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source