Results 91 to 100 of about 1,025,521 (291)

New Silica Laser-Optimized Multimode Optical Fibers with Extremely Enlarged 100-μm Core Diameter for Gigabit Onboard and Industrial Networks

Fibers, 2020
We present new type of silica graded index laser-optimized multimode optical fibers (LOMF) with extremely enlarged core diameter up to 100 μm and “typical” “telecommunication” cladding diameter 125 μm. This optical fiber
Vladimir A. Burdin, Michael V. Dashkov, Vladimir V. Demidov, Konstantin V. Dukelskii, Alexander S. Evtushenko, Artem A. Kuznetsov, Alexandra S. Matrosova, Oleg G. Morozov, Egishe V. Ter-Nersesyants, Alexander A. Vasilets, Elena S. Zaitseva, Alexander E. Zhukov, Anton V. Bourdine   +12 more
doaj   +1 more source

Time-resolved Raman Spectroscopy of Optical Phonons in Graphite: Phonon Anharmonic Coupling and Anomalous Stiffening

, 2009
Time-resolved Raman spectroscopy has been applied to probe the anharmonic coupling and electron-phonon interaction of optical phonons in graphite. From the decay of the transient anti-Stokes scattering of the G-mode following ultrafast excitation, we ...
Daohua Song, Hugen Yan, Ioannis Chatzakis, Janina Maultzsch, Kin Fai Mak, Tony F. Heinz   +5 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Nonlinear regime of the mode-coupling instability in 2D plasma crystals

, 2014
The transition between linear and nonlinear regimes of the mode-coupling instability (MCI) operating in a monolayer plasma crystal is studied. The mode coupling is triggered at the centre of the crystal and a melting front is formed, which travels ...
Couëdel, L., Ivlev, A. V., Morfill, G. E., Nosenko, V., Röcker, T. B., Thomas, H. M., Zhdanov, S. K.   +6 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Metastability, Mode Coupling and the Glass Transition

, 1994
Mode coupling theory (MCT) has been successful in explaining the observed sequence of time relaxations in dense fluids. Previous expositions of this theory showing this sequence have required the existence of an ideal glass transition temperature $T_0 ...
Cohen, Das, Das, Das, Dixon, Doster, Doster, Fleming, Fuchs, Gene F. Mazenko, Götze, Götze, Götze, Götze, Götze, Herring, Joonhyun Yeo, Kim, Kim, Kim, Kim, Leutheusser, Li, Li, Martin, Martin, Mazenko, Meizei, Petry, Richter, Schönhals, Sidebottom, Sidebottom, Sjögren, Taborek, Tao, Valls, van Megan   +37 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source