Results 41 to 50 of about 9,037 (292)
Elastic-plastic analysis of combined mode I, II and III crack-tip fields under small-scale yielding conditions [PDF]
, 1992 Within the context of the small-strain approach, combined mode I, II and III near-tip fields of stationary cracks in power-law hardening materials are investigated.
C. F. Shih +3 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
LubricantsTo investigate the propagation behavior of thermal cracks on the wheel tread under the conditions of long downhill ramps, a three-dimensional finite element model of a 1/16 wheel, including an initial thermal crack, was developed using the finite element
Jinyu Zhang +3 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Journal of the Society of Materials Science, Japan, 2007 * Compressive loading tests using acrylic acid resin and mortar specimens are conducted to research the fracture of materials with a macroscopic discontinuity under the compression loading in this study. The new types of speci- men shape that can produce mode Ⅱ and mode Ⅲ deformation are used.
HASHIMOTO, Ken-ichi +2 more
openaire +2 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Finite element analysis of the thermomechanical behavior of metal matrix composites (MMC)
Fracture and Structural Integrity, 2020 In this work the finite element method (FEM) was used to analyze the mechanical behavior of the composite materials subjected to the mechanical loading.
Zaoui Bouchra +3 more
doaj +1 more source
Study of mixed mode fracture toughness and fracture trajectories in gypsum interlayers in corrosive environment [PDF]
Royal Society Open Science, 2018 Based on the engineering background of water dissolving mining for hydrocarbon storage in multi-laminated salt stratum, the mixed mode fracture toughness and fracture trajectory of gypsum interlayers soaked in half-saturated brine at various temperatures
Bao Xiankai, Tao Meng, Zhao Jinchang
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Propagation Behavior of Mode II and Mode III Fatigue Cracks in SS400 Carbon Steel [PDF]
Fatigue characteristics are of fundamental importance when choosing a structural materials, especially when deciding upon the materials for reactor structure where long-term safety is primary importance.
大滝, 秀治 +5 more
core +1 more source