Results 81 to 90 of about 805,333 (299)
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Ensemble All Time-Scale Decomposition Method and Its Application in Bevel Gear Fault Diagnosis
All time-scale decomposition (ATD) is a non-parametric adaptive signal decomposition method, which relies on zero-crossing points and extreme points to jointly construct the baseline, achieving the suppression of modal mixing caused by the proximity of ...
Zhengyang Cheng +4 more
doaj +1 more source
Based on Multi-Masking Empirical Mode Decomposition (MMEMD) and fuzzy c-means (FCM) clustering, a new method of wind turbine bearing fault diagnosis FCM-MMEMD is proposed, which can determine the fault accurately and timely.
Yongtao Hu +5 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Deep Neural Network-Based Empirical Mode Decomposition for Motor Imagery EEG Classification
Motor imagery refers to the brain’s response during the mental simulation of physical activities, which can be detected through electroencephalogram (EEG) signals.
Hyunsoo Yu +5 more
doaj +1 more source
Strain Mode of General Flow: Characterization and Implications for Flow Pattern Structures
Understanding the mixing capability of mixing devices based on their geometric shape is an important issue both for predicting mixing processes and for designing new mixers.
Kajiwara, Toshihisa +2 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A method for detection of Mode-Mixing problem. [PDF]
Erdiş A, Akif Bakir M, I Jaiteh M.
europepmc +1 more source
Growth rate of Rayleigh-Taylor turbulent mixing layers with the foliation approach
For years, astrophysicists, plasma fusion and fluid physicists have puzzled over Rayleigh-Taylor turbulent mixing layers. In particular, strong discrepancies in the growth rates have been observed between experiments and numerical simulations.
A. Llor +4 more
core +1 more source

