Results 101 to 110 of about 431,603 (313)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Restrained Edges Effect on the Dynamics of Thermoelastic Plates under Different End Conditions
Frequency equations for rectangular plate model with and without the thermoelastic effect for the cases are: all edges are simply supported, all edges are clamped and two opposite edges are clamped others are simply supported. These were obtained through
Adnan N. Jameel +2 more
doaj +2 more sources
Shape Morphing Using PDE Surfaces
YesA methodology for shape morphing using partial differential equation (PDE) surfaces is presented in this work. The use of the PDE formulation shows how shape morphing can be based on a boundary-value approach by which intermediate shapes can be ...
Willis, P. +3 more
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Full-Field Vibration Measurement Using Camera Through Shearlet System
Traditionally, vibration measurement is done using an accelerometer or Laser Doppler Vibrometer, which is an intrusive and single point measurement respectively.
Wee C.A., Ngali M. Z.
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Imaging morphological details and pathological differences of red blood cells using tapping-mode AFM [PDF]
The surface topography of red blood cells (RBCs) was investigated under nearphysiological conditions using atomic force microscopy (AFM). An immobilization protocol was established where RBCs are coupled via molecular bonds of the membrane glycoproteins ...
Zhu, Rong +9 more
core +1 more source
An Investigation of Complex Mode Shapes
This paper presents an investigation of complex mode shape analysis caused by non-linear damping. Nowadays, most academics are accustomed to complex mode shapes, which are a characteristic of most axisymmetric structures. The topic was deeply investigated during the 1980s, sparking the sharpest debates about their physical existence or not.
Verhoeven, C. +4 more
openaire +1 more source

