Results 101 to 110 of about 1,998,737 (342)
Reversibility of Arctic Sea Ice Retreat - A Multi-Scale Modeling Approach [PDF]
, 2012 Arctic summer sea ice has been retreating rapidly over past decade. Climate model projections show further retreat under typical forcing scenarios. The mode of the retreat is a matter of debate.
Mueller-Stoffels, M.
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie ŚrodowiskaThe research described in this paper aims to enhance the structural health monitoring (SHM) of highway bridges by integrating numerical simulations with experimental data.
Om Narayan Singh, Kaushik Dey
doaj +1 more source
Analysis of structural dynamic data from Skylab. Volume 2: Skylab analytical and test model data [PDF]
The orbital configuration test modal data, analytical test correlation modal data, and analytical flight configuration modal data are presented. Tables showing the generalized mass contributions (GMCs) for each of the thirty tests modes are given along ...
Demchak, L., Harcrow, H.
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Multiple Damage Detection of an Offshore Helideck through the Two-Step Artificial Neural Network Based on the Limited Mode Shape Data. [PDF]
Sensors (Basel), 2021 Kim B, Kim C, Ha SH.
europepmc +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Cascaded-mode interferometers: Spectral shape and linewidth engineering
Science AdvancesInterferometers are essential tools for measuring and shaping optical fields, widely used in optical metrology, sensing, laser physics, and quantum mechanics. They superimpose waves with a mutual phase delay, modifying light intensity. A frequency-dependent phase delay enables spectral shaping for filtering, routing, wave shaping, or multiplexing ...
Lu, Jinsheng +4 more
openaire +3 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source