Results 41 to 50 of about 797,470 (304)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Functional model-based curve clustering for discovering temporal patterns in chronological corpora [PDF]

, 2012
In many applications of textual analysis corpora are characterized by a temporal structure, i.e. they include texts which have a chronological order (e.g.: political discourses, institutional documents, articles published in newspapers, messages posted ...
Trevisani, Matilde, TUZZI, ARJUNA, A. Tuzzi   +2 more
core  

Large scale clustering of protein sequences with FORCE - a layout based heuristic for weighted cluster editing [PDF]

, 2007
Wittkop T, Baumbach J, Lobo FP, Rahmann S. Large scale clustering of protein sequences with FORCE - a layout based heuristic for weighted cluster editing. BMC Bioinformatics.
Wittkop, Tobias, Tobias Wittkop, Baumbach Jan, Lobo Francisco P, Sven Rahmann, Francisco P Lobo, Rahmann Sven, Jan Baumbach, Baumbach, Jan, Wittkop Tobias, Lobo, Francisco P., Rahmann, Sven   +11 more
core   +2 more sources

Human-Interpretable Time-Series Feature Extraction Using Model-Based Clustering

IEEE Access
Feature extraction is an essential task for Deep Neural Networks (DNNs), as high-dimensional data are often available and filtering can highlight relevant patterns for the reconstruction or forecasting of a target.
Joao Eduardo Hoffmann, Asad Waqar Malik, Max Mauro Dias Santos, Joao Francisco Justo   +3 more
doaj   +1 more source

Fair Model-based Clustering

Proceedings of the AAAI Conference on Artificial Intelligence
The goal of fair clustering is to find clusters such that the proportion of sensitive attributes (e.g., gender, race, etc) in each cluster is similar to the proportion of the entire data. Various fair clustering algorithms have been proposed, which modify standard K-means clustering to satisfy a given fairness constraint.
Jinwon Park, Kunwoong Kim, Jihu Lee, Yongdai Kim   +3 more
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

blockcluster: An R Package for Model-Based Co-Clustering

Journal of Statistical Software, 2017
Simultaneous clustering of rows and columns, usually designated by bi-clustering, coclustering or block clustering, is an important technique in two way data analysis.
Parmeet Singh Bhatia, Serge Iovleff, Gérard Govaert   +2 more
doaj   +1 more source

Model-Based Clustering for Social Networks [PDF]

Journal of the Royal Statistical Society Series A: Statistics in Society, 2007
SummaryNetwork models are widely used to represent relations between interacting units or actors. Network data often exhibit transitivity, meaning that two actors that have ties to a third actor are more likely to be tied than actors that do not, homophily by attributes of the actors or dyads, and clustering.
Handcock, Mark S., Raftery, Adrian, Tantrum, Jeremy   +2 more
openaire   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source