Results 61 to 70 of about 1,500,611 (328)
Semi-supervised model-based clustering with controlled clusters leakage
, 2017 In this paper, we focus on finding clusters in partially categorized data sets. We propose a semi-supervised version of Gaussian mixture model, called C3L, which retrieves natural subgroups of given categories. In contrast to other semi-supervised models,
Struski, Łukasz +2 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
A Bayesian Approach for Clustering Constant-Wise Change-Point Data
StatsChange-point models deal with ordered data sequences. Their primary goal is to infer the locations where an aspect of the data sequence changes. In this paper, we propose and implement a nonparametric Bayesian model for clustering observations based on ...
Ana Carolina da Cruz +1 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Model-based co-clustering for hyperspectral images
Journal of Spectral Imaging, 2016 A model-based co-clustering algorithm for hyperspectral images is presented. This algorithm, which relies on the probabilistic latent block model for continuous data, aims to cluster both the pixels and the spectral features of the images.
Julien Jacques, Cyril Ruckebusch
doaj +1 more source
Application of Microsatellite Markers for Identification and Registration of Pistachio Cultivars [PDF]
مجله بیوتکنولوژی کشاورزی, 2015 Due to complex identification of young pistachio cultivars) Pistacia vera L.) using morphological traits, advance molecular tools have provided a new prospect for DNA fingerprinting.
Mohsen Mardi +2 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
A formal algorithm for verifying the validity of clustering results based on model checking. [PDF]
PLoS ONE, 2014 The limitations in general methods to evaluate clustering will remain difficult to overcome if verifying the clustering validity continues to be based on clustering results and evaluation index values.
Shaobin Huang +4 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source