Results 91 to 100 of about 9,098,363 (304)
Rapid Experimental Protocol for PMSM via MBD: Modeling, Simulation, and Experiment
ComputersAs control algorithms evolve, their enhanced performance is often accompanied by increased complexity, reaching a point where practical experimentation becomes unfeasible.
Mingyuan Hu +4 more
doaj +1 more source
, 2012 This is a book of edited articles and design projects from five years of collaborative international design projects in developed and developing economies, including China, Thailand, Ghana and Japan.
Childs, Peter +3 more
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PowerPlanningDL: Reliability-Aware Framework for On-Chip Power Grid Design using Deep Learning
, 2020 With the increase in the complexity of chip designs, VLSI physical design has become a time-consuming task, which is an iterative design process. Power planning is that part of the floorplanning in VLSI physical design where power grid networks are ...
kingma, lin, mohammad fawaz, ng
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Creating a Model-Based Learning Environment in BIM Education through Case Studies
Journal of Architectural Sciences and ApplicationsAs demand in the construction industry continues to rise globally, universities have shown an increased interest in Building Information Modeling (BIM) education, leading to accelerated curriculum development studies.
Semih Göksel Yıldırım
doaj +1 more source
A Model for Quality Optimization in Software Design Processes [PDF]
, 2005 The main objective of software engineers is to design and implement systems that implement all functional and non-functional requirements. Unfortunately, it is very difficult or even generally impossible to deliver a software system that satisfies all ...
Aksit, Mehmet +2 more
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The design research pyramid: a three layer framework [PDF]
, 2007 To support knowledge-based design development, considerable research has been conducted from various perspectives at different levels. The research on knowledge-based design support systems, generic design artefact and design process modelling, and the ...
Duffy, Alexander, Wang, Wenjuan
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