Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Interpretation of a General Model for Inventive Problems, the Generalized System of Contradictions [PDF]
, 2009 Organised by: Cranfield UniversityDesign of technical systems implies either optimisation or inventive problems resolution. Resolution tools and methods exist for each kind of problems.
Dubois, S., De Guio, R., Rasovska, I.
core
09073 Abstracts Collection – Model-Based Design of Trustworthy Health Information Systems
, 2009 The Dagstuhl Seminar ``Model-Based Design of Trustworthy Information Systems'' took place from February 11th to February 14th, 2009, at the International Conference and Research Center Schloss Dagstuhl.
Winter, Alfred +3 more
core +1 more source
Model-Based Design to Enhance Neotissue Formation in Additively Manufactured Calcium-Phosphate-Based Scaffolds. [PDF]
J Funct Biomater, 2023 Liang B +8 more
europepmc +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
A model-based approach to hypermedia design. [PDF]
This paper introduces the MESH approach to hypermedia design, which combines established entity-relationship and object-oriented abstractions with proprietary concepts into a formal hypermedia data model. Uniform layout and link typing specifications can
Lemahieu, Wilfried
core
Design and Real-time Implementation of the Adaptive-Neuro-Fuzzy Controller for a Temperature Control System using Model-Based Design [PDF]
فصلنامه علوم و فناوری فضایی, 2018 In this paper, an adaptive-neuro-fuzzy controller is implemented online for a temperature control system using model-based design. First, the time domain identification approaches are utilized for the dynamic model identification.
Alireza Sharifi +2 more
doaj
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
JANUS: an open-source 3D printable perfusion bioreactor and numerical model-based design strategy for tissue engineering. [PDF]
Front Bioeng Biotechnol, 2023 Meneses J +5 more
europepmc +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source