Results 131 to 140 of about 5,793,293 (269)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Model-based decoupling control method for dual-drive gantry stages : A case study with experimental validations

, 2013
La version éditeur de cet article est disponible à l'adresse suivante : http://dx.doi.org/10.1016/j.conengprac.2012.10.010Industrial motion control of dual–drive gantry stages is usually performed by position controllers acting independently on each ...
COLEMAN, Ralph, GOMAND, Julien, KESTELYN, Xavier, BARRE, Pierre-Jean, GARCÍA-HERREROS, Iván   +4 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Sound Based Music Design Demonstration

, 2022
The following video demonstrates a novel approach using a Digital Audio Workstation (DAW) as a new form of pedagogic activity for higher education. This demonstration sits within a set of pieces that I refer to as a Smear Symphony.
Boon, H.
core  

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Forward dynamics simulation for analyzing interactions with passive lower-limb assistive devices via optimization of physical posture

Journal of Biomechanical Science and Engineering
Forward dynamics simulations can significantly reduce the development costs associated with new wearable assistive devices by minimizing the need for prototyping and experimentation.
Naoto HARAGUCHI, Kazunori HASE
doaj   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source

Toward proactive eco-design based on engineer and eco-designer's software interface modeling [PDF]

, 2011
Lien vers la version éditeur: http://www.designsociety.org/publication/30585/toward_proactive_eco-design_based_on_engineer_and_eco-designers_software_interface_modelingIntegrating environmental concerns as well as other constrains (cost, quality, etc ...
RIO, Maud, REYES, Tatiana, ROUCOULES, Lionel   +2 more
core  

Model-Based Design and Optimization of Blood Oxygenators. [PDF]

J Med Device, 2020
He G, Zhang T, Zhang J, Griffith BP, Wu ZJ.   +4 more
europepmc   +1 more source