Results 91 to 100 of about 6,641,478 (335)

Model based system engineering approach of a lightweight embedded TCP/IP

, 2011
The use of embedded software is growing very rapidly. Accessing the internet is a necessary service which has large range of applications in many fields. The Internet is based on TCP/IP which is a very important stack.
Hassan, Ahmed E., Rashed, M. Z., Sharaf, Ahmed I.   +2 more
core   +1 more source

A synthesis of logic and bio-inspired techniques in the design of dependable systems [PDF]

, 2016
Much of the development of model-based design and dependability analysis in the design of dependable systems, including software intensive systems, can be attributed to the application of advances in formal logic and its application to fault forecasting ...
Azevedo, Luis, Bottaci, Leonardo, Kabir, Sohag, Papadopoulos, Yiannis, Parker, David, Sharvia, Septavera, Sorokos, Ioannis, Walker, Martin   +7 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Adaptable MBSE Problem Definition with ARMADE: Perspectives from Firefighting and AAM SoS Environments

Engineering Proceedings
Model-based systems engineering (MBSE) offers significant advantages over traditional document-based approaches, particularly in improving the clarity, traceability, and efficiency of requirements engineering (RE).
Adrian Chojnacki, Giuseppa Donelli, Luca Boggero, Prajwal S. Prakasha, Björn Nagel   +4 more
doaj   +1 more source

Fusing Quantitative Requirements Analysis with Model-based Systems Engineering [PDF]

, 2006
A vision is presented for fusing quantitative requirements analysis with model-based systems engineering. This vision draws upon and combines emergent themes in the engineering milieu.
Cornford, Steven L., Feather, Martin S., Heron, Vance A., Jenkins, J. Steven   +3 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Relational Approach to Knowledge Engineering for POMDP-based Assistance Systems as a Translation of a Psychological Model [PDF]

, 2012
Assistive systems for persons with cognitive disabilities (e.g. dementia) are difficult to build due to the wide range of different approaches people can take to accomplishing the same task, and the significant uncertainties that arise from both the ...
Czarnuch, Stephen, Grzes, Marek, Hoey, Jesse, Jackson, Dan, Khan, Shehroz, Mihailidis, Alex, Monk, Andrew   +6 more
core   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Engineering Systems with Standards and Digital Models: Development of a 15288-SysML Grid

Systems
The paradigm shift that has spurred the fourth industrial revolution, in what is termed Industry 4.0, has ushered in the need to adopt digital technologies throughout the worldwide industrial base to support system design efforts. The adoption of digital
Kevin MacG. Adams, Irfan Ibrahim, Steven Krahn   +2 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source