Results 111 to 120 of about 11,397 (304)

Model-Driven Methodology for Rapid Deployment of Smart Spaces Based on Resource-Oriented Architectures

Sensors, 2012
Advances in electronics nowadays facilitate the design of smart spaces based on physical mash-ups of sensor and actuator devices. At the same time, software paradigms such as Internet of Things (IoT) and Web of Things (WoT) are motivating the creation of
José R. Casar, Josué Iglesias, Ana M. Bernardos, Iván Corredor   +3 more
doaj   +1 more source

Model Transformations in MT [PDF]

, 2007
Model transformations are recognised as a vital aspect of Model Driven Development,but current approaches cover only a small part of the possible spectrum.
Laurence Tratt, Tratt, Laurence
core   +1 more source

A Brain‐Penetrant Nanobody Reveals GSK3β‐Driven Proline‐Directed Phosphorylation as a Master Regulator of Ischemic Neurodegeneration

Advanced Science, EarlyView.
A brain‐targeted nanoparticle enables delivery of a therapeutic nanobody (Nb.29E9) that inhibits pathogenic GSK3β signaling. This intervention restores AMPK/mTORC1/TGFβ homeostasis, attenuates neuroinflammation and oxidative stress, and promotes long‐term functional recovery after ischemic stroke.
Lan Li, Muyang Li, Lei Sun, Ying Yang, Yuanshun Wu, Ziyi Yin, Anni Wang, Peiyang Zhou, Shaoxiang Luo, Jian Chen, Jun Qin, Zhibing Ai, Zilong Yuan, Zhiqiang Dong, Min Zhang   +14 more
wiley   +1 more source

Model Driven Architecture and Modeling Driven Software Development [PDF]

The monography is a proceeding of the papers presented at the 3rd 3rd International Workshop on Model Driven Architecture and Modeling Driven Software Development In conjinction with the 6th International Conference on Evaluation of Novel Approaches to ...
Ņikiforova, Oksana, Osis, Jānis
core  

Preliminary findings from a survey on the MD state of the practice [PDF]

, 2011
In the context of an Italian research project, this paper reports on an on-line survey, performed with 155 software professionals, with the aim of investigating about their opinions and experiences in modeling during software development and Model-driven
Ricca F., Tiso A., Tomassetti, Federico Cesare Argentino, Reggio, G., REGGIO, GIANNA, Ricca, F., Tiso, A., Gianna Reggio, Reggio G., F. Tomassetti, Federico Tomassetti, RICCA, FILIPPO, Alessandro Tiso, Filippo Ricca, M. Torchiano, A. Tiso, Torchiano, Marco, Marco Torchiano   +17 more
core   +1 more source

Designer Dynamic DNA Nanoaggregate in Living Cell for Mitochondrial Energy Restriction

Advanced Science, EarlyView.
This study presents the Tech‐tetrahedron, a designer dynamic DNA nanoaggregate engineered for precise mitochondrial energy restriction. Its trinity‐functionalized design integrates navigable unit, telomerase‐activated latch, and self‐assembly module.
Ruijia Deng, Jing Sheng, Ben Niu, Wenjuan Fu, Yingjie Yang, Zuowei Xie, Shuang Xie, Yunxuan He, Meilin Gong, Jue Wang, Yan Pi, Ming Chen, Kai Chang   +12 more
wiley   +1 more source

Ontology-based patterns for the integration of business processes and enterprise application architectures [PDF]

, 2010
Increasingly, enterprises are using Service-Oriented Architecture (SOA) as an approach to Enterprise Application Integration (EAI). SOA has the potential to bridge the gap between business and technology and to improve the reuse of existing applications
Pahl, Claus, Gacitua-Decar, Veronica
core  

Inside‐Outside ROS Therapeutic Strategy Based on Piezoelectric Nano‐Urchin for Drug‐Resistant Bacteria Biofilm Infections

Advanced Science, EarlyView.
The contribution of this study lies not only in enabling effective treatment of drug‐resistant biofilm infections, but also in establishing a transferable therapeutic paradigm: Ultrasound‐triggered mechanical forces synergistically enhance piezoelectric polarization and nanozyme activity, driving functional ROS generation inside and outside biofilms ...
Xinjian Guo, Jin Yang, Mengjie An, Bingjie Lin, Tao Liu, Limin Zhang   +5 more
wiley   +1 more source

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng, Tristan Juin Han Chang, Xinchao Li, Zhongqi Zhou, Chung Tin, Kenward Vong, Pierre Karam, Pik Kwan Lo   +7 more
wiley   +1 more source

Yekta: A low-code framework for automated test models generation

SoftwareX
The methodology under the term model-based software engineering (MBSE) gained importance already around 20 years ago, after the publication of the Model-Driven Architecture (MDA) initiative by the Object Management Group (OMG).
Meysam Karimi, Shekoufeh Kolahdouz-Rahimi, Javier Troya   +2 more
doaj   +1 more source