Results 151 to 160 of about 2,777,627 (313)
LocSys: A Low-Code Paradigm for the Development of Cyber-Physical Applications
SensorsApplication development for the cyber-physical systems (CPS) domain is considered a quite complex procedure, since it not only requires a high level of expertise but also deep knowledge of heterogeneous domains.
Konstantinos Panayiotou +2 more
doaj +1 more source
DATASET2050 D2.2 - Data-driven Model [PDF]
, 2016 The purpose of this document, Deliverable 2.2, is to build the structure and specifications of the DATASET2050 data driven model. The door-to-door process is complex and therefore direct performance measurement of the process cannot be done due to ...
Perez, D. +5 more
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Agile Model Driven Development of Electronic Health Record-Based Specialty Population Registries. [PDF]
IEEE EMBS Int Conf Biomed Health Inform, 2016 Kannan V, Fish JC, Willett DL.
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Large language model driven development of turbulence models
FlowArtificial intelligence (AI) has achieved human-level performance in specialised tasks such as Go, image recognition and protein folding, raising the prospect of an AI singularity – where machines not only match, but surpass human reasoning.
Zhongxin Yang +3 more
doaj +1 more source
Archetype Model-Driven Development Framework for EHR Web System. [PDF]
Healthc Inform Res, 2013 Kobayashi S, Kimura E, Ishihara K.
europepmc +1 more source
Reactive transport simulations of microbial activity and biogeochemical transformations in porous environments - development and application of a pore-network model [PDF]
, 2014 The focus of this study was on the development and application of a model, describing the micro-scale, flexible enough to consider any arbitrary number of reactions, and able to simulate reactive transport of chemicals and microorganisms in the presence ...
Geochemistry +2 more
core
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source