On the Tool Chain for Model Driven Architecture and Model Driven Development: Drawing a Distinction [PDF]
Model Driven Architecture (MDA), introduced by Object Management Group in 2001, is the primary example of Model Driven Development (MDD), aimed to satisfy the needs of the modern software industry. The main idea of MDA is to define software solution in a
Čerņičkins, Antons +2 more
core
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Adapting Software Development Process towards the Model Driven Architecture [PDF]
Model driven architecture (MDA) is increasingly gaining the attention of both research communities and industry. MDA is a model-oriented software development paradigm, which can be applied to any software development methodology.
Ņikiforova, Oksana +1 more
core
An Embedded Domain Specific Language to Model, Transform and Quality Assure Business Processes in Business-Driven Development [PDF]
In Business-Driven Development (BDD), business process models are produced by business analysts. To ensure that the business requirements are satisfied, the IT solution is directly derived through a process of model refinement.
Pace, Gordon J., Micallef, Luana
core
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Discussing the Difference between Model Driven Architecture and Model Driven Development in the Context of Supporting Tools [PDF]
Evolution of software development process, increasing complexity of software systems and appearance of necessity to construct the software systems in the manner offered by OMG’s initiative Model Driven Architecture arise developers to pay great attention
Čerņičkins, Antons +2 more
core
Model-Driven Engineering of a Railway Interlocking System [PDF]
Model-Driven Engineering (MDE) promises to enhance system development by reducing development time, and increasing productivity and quality. MDE is gaining popularity in several industry sectors, and is attractive also for critical systems where they can
PIETRANTUONO, ROBERTO +3 more
core
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
An industrial case study on using language workbench technology for realizing model-driven engineering [PDF]
Model Driven Engineering (MDE) is a proven approach to improve software development processes by automation. However, traditional development of MDE tooling requires a high upfront cost.
Krekola, M. +6 more
core

