Results 111 to 120 of about 3,656,540 (298)

Islamic development model: a shift from growth-driven to prosperity-driven model / Hassan Mad [PDF]

open access: yes, 2017
Islamic development model is nothing new. The formulation of the Medina Charter for example, is a classical case of a noble initiative taken by Prophet Muhammad (pbuh).
Mad, Hassan
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Implementation-driven of Development Planning Model [PDF]

open access: yesمدیریت دولتی
ObjectiveDespite Iran’s long history of national development planning and the considerable investment of human and financial resources, the country has not successfully realized the goals outlined in its plans.
Reza Vaezi   +3 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Applying model-driven paradigm: CALIPSOneo experience [PDF]

open access: yes, 2013
Model-Driven Engineering paradigm is being used by the research community in the last years, obtaining suitable results. However, there are few practical experiences in the enterprise field. This paper presents the use of this paradigm in an aeronautical
Escalona Cuaresma, María José   +4 more
core  

Reusing Test-Cases on Different Levels of Abstraction in a Model Based Development Tool

open access: yes, 2012
Seamless model based development aims to use models during all phases of the development process of a system. During the development process in a component-based approach, components of a system are described at qualitatively differing abstraction levels:
Alexander K. Petrenko   +4 more
core   +1 more source

Model-Driven Web Development with VisualWADE [PDF]

open access: yes, 2004
VisualWADE is a model-driven web development environment for web applications that includes model-based code generation techniques. This paper describes the capabilities of that environment and how Web applications can be generated in an automated way.
openaire   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

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