Results 101 to 110 of about 3,656,540 (298)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

INDIeAuthor: A Metamodel-Based Textual Language for Authoring Educational Courses

open access: yesIEEE Access, 2019
This paper presents the INDIeAuthor authoring tool, which has been developed at the Digital Content Production Center, Polytechnic University of Cartagena (UPCT).
Daniel Perez-Berenguer   +1 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Simulation of Road Traffic Applying Model-Driven Engineering

open access: yesAdvances in Distributed Computing and Artificial Intelligence Journal, 2016
Road traffic is an important phenomenon in modern societies. The study of its different aspects in the multiple scenarios where it happens is relevant for a huge number of problems.
Alberto FERNÁNDEZ-ISABEL   +1 more
doaj   +1 more source

Occupant behaviour in naturally ventilated and hybrid buildings [PDF]

open access: yes, 2009
Adaptive thermal comfort criteria for building occupants are now becoming established. In this paper we illustrate their use in the prediction of occupant behaviour and make a comparison with a non-adaptive temperature threshold approach.
Clarke, J.A.   +4 more
core  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Edge IoT Prototyping Using Model-Driven Representations: A Use Case for Smart Agriculture

open access: yesSensors
Industry 4.0 is positioned at the junction of different disciplines, aiming to re-engineer processes and improve effectiveness and efficiency. It is taking over many industries whose traditional practices are being disrupted by advances in technology and
Ivan Guevara   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Scale Modular Test Platform for the Characterization of PD Measuring Systems Using HFCT Sensors

open access: yesSensors
Today, online partial discharge (PD) measurements are common practice to assess the condition status of dielectrics in high-voltage (HV) electrical grids.
Eduardo Arcones   +3 more
doaj   +1 more source

Usability evaluation of the domain specific language for spatial simulation scenarios

open access: yesCogent Engineering, 2018
This article presents the results of a usability evaluation initiative conducted on the Domain Specific Language for Spatial Simulation Scenarios (short name DSL3S) and its supporting tools.
Luís Moreira de Sousa   +1 more
doaj   +1 more source

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