Results 51 to 60 of about 1,764,289 (298)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Adopting MDE for Specifying and Executing Civilian Missions of Mobile Multi-Robot Systems

open access: yesIEEE Access, 2016
Robots are meant to replace humans for a broad variety of everyday tasks, such as environmental monitoring or patrolling large public areas for security assurance.
Federico Ciccozzi   +3 more
doaj   +1 more source

Dirty engineering data-driven inverse prediction machine learning model

open access: yesScientific Reports, 2020
Most data-driven machine learning (ML) approaches established in metallurgy research fields are focused on a build-up of reliable quantitative models that predict a material property from a given set of material conditions.
Jin-Woong Lee   +5 more
doaj   +1 more source

Traceability for Model Driven, Software Product Line Engineering [PDF]

open access: yes, 2008
Traceability is an important challenge for software organizations. This is true for traditional software development and even more so in new approaches that introduce more variety of artefacts such as Model Driven development or Software Product Lines ...
Anquetil, N.   +7 more
core   +5 more sources

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

Quality-Driven Detection and Resolution of Metamodel Smells

open access: yesIEEE Access, 2019
In model-driven engineering, analogously to any software development practice, metamodel design must be accurate and performed by considering relevant quality factors, including maintainability, reusability, and understandability.
Lorenzo Bettini   +3 more
doaj   +1 more source

Model-driven engineering approach to design and implementation of robot control system [PDF]

open access: yes, 2013
In this paper we apply a model-driven engineering approach to designing domain-specific solutions for robot control system development. We present a case study of the complete process, including identification of the domain meta-model, graphical notation
Trojanek, Piotr
core  

Model Driven Development of m-Health Systems (with a Touch of Formality) [PDF]

open access: yes, 2006
We propose a model driven design and development methodology augmented with formal validation and verification (V&V) for the development of mobile health systems.
Jones, Val
core   +4 more sources

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi   +5 more
wiley   +1 more source

Model-Driven Approaches for Conversational Agents Development: A Systematic Mapping Study

open access: yesIEEE Access, 2023
Conversational agents are a piece of software widely used nowadays in several domains, such as e-commerce, customer support, education, among others. To build one, proficiency in distinct areas of knowledge is necessary. Moreover, its development demands
Angel Antonio Martinez-Garate   +3 more
doaj   +1 more source

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